SCHEMBL345326

SCHEMBL345326

C=C(C)C(=O)Nc1cc(C(C)(C)CCCCC)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 14/20 0.35
CNR1 P21554 13/20 0.35
GPR18 Q14330 3/20 0.35
GPR55 Q9Y2T6 3/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
POLB P06746 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
TRPV1 Q8NER1 1/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16191289 0.86 POLB (0.36) NPC1RAB9APOLBMEN1USP2
SCHEMBL345190 0.85 CNR2 (0.34) CNR2CNR1GPR18GPR55NPC1
SCHEMBL17941214 0.85 MAPK14 (0.40) CNR2CNR1MAPTALDH1A1KDM4E
SCHEMBL4441567 0.85 NPC1 (0.39) NPC1RAB9APOLBMEN1USP2
SCHEMBL345788 0.83 NPC1 (0.33) CNR2CNR1NPC1RAB9APOLB
SCHEMBL508930 0.81 NPC1 (0.34) CNR2CNR1NPC1RAB9APOLB
SCHEMBL4615162 0.81 CNR1 (0.36) CNR2CNR1GPR18GPR55NPC1
SCHEMBL13370057 0.81 CNR1 (0.38) CNR2CNR1GPR18GPR55NPC1
SCHEMBL1099131 0.80 POLB (0.34) CNR2CNR1GPR18GPR55NPC1
SCHEMBL9408777 0.80 CNR2 (0.36) CNR2CNR1GPR18GPR55NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2416381-A1 PROTECTIVE SHEET FOR SOLAR CELL MODULE AND SOLAR CELL MODULE LINTEC Corporation (JP) 2012-02-08 EP disclosed
US-20120012164-A1 PROTECTIVE SHEET FOR SOLAR CELL MODULE AND SOLAR CELL MODULE LINTEC CORPORATION (JP) 2012-01-19 US disclosed
US-8003222-B2 Resin composition for forming ultraviolet absorbing layer and laminate comprising ultraviolet absorbing layer NIPPON SHOKUBAI CO., LTD. (JP) 2011-08-23 US disclosed
US-20090110936-A1 Resin Composition for Forming Ultraviolet Absorbing Layer and Laminate Comprising Ultraviolet Absorbing Layer NIPPON SHOKUBAI CO., LTD. (JP) 2009-04-30 US disclosed
WO-2006090917-A2 ULTRAVIOLET ABSORBING POLYMER FOR HIGH LIGHT RESISTANT RECORDING MATERIALS NIPPON SHOKUBAI CO., LTD. (JP) 2006-08-31 WO disclosed