SCHEMBL4615162

SCHEMBL4615162

CCCCCC(C)(C)c1cc(Nc2nc(Nc3cc(C(C)(C)CCCCC)cc(-n4nc5ccccc5n4)c3O)nc(Nc3cc(C(C)(C)CCCCC)cc(-n4nc5ccccc5n4)c3O)n2)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 16/20 0.36
CNR2 P34972 14/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
GPR18 Q14330 3/20 0.33
GPR55 Q9Y2T6 3/20 0.33
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105359 0.85 NPC1 (0.39) NPC1RAB9APOLBLMNA
SCHEMBL7588136 0.83 CNR1 (0.44) CNR1CNR2NPC1RAB9AGPR18
SCHEMBL2464792 0.83 CNR2 (0.44) CNR1CNR2NPC1RAB9AGPR18
SCHEMBL673359 0.82 CNR1 (0.40) CNR1CNR2NPC1RAB9AGPR18
SCHEMBL2467398 0.82 CNR2 (0.46) CNR1CNR2NPC1RAB9AGPR18
SCHEMBL22289027 0.81 CNR1 (0.42) CNR1CNR2NPC1RAB9AGPR18
SCHEMBL258641 0.81 CNR1 (0.41) CNR1CNR2NPC1RAB9AGPR18
SCHEMBL139856 0.81 CNR1 (0.47) CNR1CNR2NPC1RAB9AGPR18
SCHEMBL17941214 0.81 MAPK14 (0.40) CNR1CNR2
SCHEMBL345326 0.81 CNR2 (0.35) CNR1CNR2NPC1RAB9AGPR18

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1618927-B1 Sunscreen compositions containing a triazine filter solubilised by a mixture of an arylalkyl benzoate derivative and an amide-modified oil; uses in cosmetics OREAL (FR) 2012-08-01 EP claimed
EP-1353642-B1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING AN AMPHIPHILIC COPOYLMER COMPRISING 2-ACRYLAMIDO-2-PROPANESULFONIC AND (METH)ACRYLATES OREAL (FR) 2008-05-07 EP claimed
EP-1796622-B1 COSMETIC COMPOSITIONS CONTAINING A TRIAZINE DERIVATIVE, AN AMIDE-BASED OIL AND A EUTECTIC MIXTURE OF N-BUTYL-PHTHALIMIDE/ISOPROPYLPHTHALIMIDE OREAL (FR) 2008-01-23 EP claimed
US-20070140997-A1 Photoprotective compositions containing a triazine derivative, an amide-based oil and a eutectic mixture of n-butylphthalimide/isopropylphthalimide L'OREAL (FR) 2007-06-21 US claimed
EP-1796622-A1 COSMETIC COMPOSITIONS CONTAINING A TRIAZINE DERIVATIVE, AN AMIDE-BASED OIL AND A EUTECTIC MIXTURE OF N-BUTYL-PHTHALIMIDE/ISOPROPYLPHTHALIMIDE L'OREAL (FR) 2007-06-20 EP claimed
US-7166274-B2 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds L'OREAL (FR) 2007-01-23 US claimed
EP-1430881-B1 Compositions comprising a triazine derivative solubilized in a eutectic mixture of n-butylphthalimide/isopropylphthalimide and cosmetic use OREAL (FR) 2006-09-27 EP claimed
US-7045120-B2 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers L'OREAL (FR) 2006-05-16 US claimed
WO-2006003028-A1 COSMETIC COMPOSITIONS CONTAINING A TRIAZINE DERIVATIVE, AN AMIDE-BASED OIL AND A EUTECTIC MIXTURE OF N-BUTYL-PHTHALIMIDE/ISOPROPYLPHTHALIMIDE L'OREAL (FR) 2006-01-12 WO claimed
WO-2006003020-A1 COMPOSITIONS CONTAINING A TRIAZINE DERIVATIVE, AN ARYLALKYL BENZOATE DERIVATIVE AND A EUTECTIC N-BUTYLPHTHALIMIDE/ISOPROPYLPHTHALIMIDE MIXTURE; COSMETIC USES THEREOF L'OREAL (FR) 2006-01-12 WO claimed
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL S.A. (FR) 2004-04-15 US claimed
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SOCIETE L'OREAL S.A. (FR) 2004-03-11 US claimed
EP-0944624-B1 INSOLUBLE S-TRIAZINE DERIVATIVES AND THEIR USE AS UV FILTERS OREAL (FR) 2003-11-05 EP claimed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US claimed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 US claimed
EP-1093796-B1 Emulsions containing one or more insoluble organic UV-filter and an associative polymer OREAL (FR) 2003-02-05 EP claimed
US-6509008-B1 Cosmetic and dermatological sun screen agent with higher protection factor L'OREAL (FR) 2003-01-21 US claimed
US-6361764-B2 ULTRAVIOLET LIGHT SCREENING AGENTS; COSMETICS SOCIETE L'OREAL S.A. (FR) 2002-03-26 US claimed
EP-1093797-B1 Process for the photostabilisation of sunscreens derived from dibenzoylmethane by an insoluble organic filter OREAL (FR) 2002-02-20 EP claimed
US-20020010179-A1 Novel insoluble S-triazine derivatives, process for their preparation, compositions containing them and uses thereof RICHARD HERVE (FR) 2002-01-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070140997-A1 Photoprotective compositions containing a triazine derivative, an amide-based oil and a eutectic mixture of n-butylphthalimide/isopropylphthalimide CRYZ, ERCC2, MITF CNR1 3327/4885CNR2 1861/4885NPC1 3794/4885
US-20020010179-A1 Novel insoluble S-triazine derivatives, process for their preparation, compositions containing them and uses thereof TST, TYR, TPST2 CNR1 4633/4885CNR2 4146/4885NPC1 3874/4885
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, DSG1, PCNA CNR1 4173/4885CNR2 3770/4885NPC1 3176/4885
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SUCLG1, CUTA, DLD CNR1 4476/4885CNR2 4093/4885NPC1 2529/4885
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS HADHB, SDHA, ERCC4 CNR1 4763/4885CNR2 4575/4885NPC1 3007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.