Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28432909 | 0.81 | AHR (0.45) | GRM5MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27070680 | 0.79 | RAB9A (0.47) | MAPTSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL31501737 | 0.79 | ALDH1A1 (0.53) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL19814079 | 0.79 | ALDH1A1 (0.53) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL25296424 | 0.79 | MAPT (0.43) | GRM5MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2562927 | 0.79 | NOTUM (0.46) | GRM5SMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL18373402 | 0.79 | NR4A2 (0.41) | GRM5MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27631421 | 0.78 | SMN1; SMN2 (0.45) | GRM5MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2322004 | 0.78 | NPC1 (0.69) | GRM5MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30462821 | 0.78 | MAPT (0.42) | GRM5MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1326317-A | Combinations of herbicides and safeners | AVENTIS CROPSCIENCE GMBH (DE) | 2001-12-12 | — | — | CN | claimed |
| EP-0561970-B1 | ANTIDOTING HERBICIDAL 3-ISOXAZOLIDINONE COMPOUNDS | ZENECA INC (US) | 1995-01-18 | — | — | EP | claimed |
| EP-0561970-A1 | ANTIDOTING HERBICIDAL 3-ISOXAZOLIDINONE COMPOUNDS. | ZENECA INC (US) | 1993-09-29 | — | — | EP | claimed |
| WO-1992010095-A1 | ANTIDOTING HERBICIDAL 3-ISOXAZOLIDINONE COMPOUNDS | ZENECA INC. (US) | 1992-06-25 | — | — | WO | claimed |
| CN-110461157-A | Herbicidal mixture | BAYER AG | 2019-11-15 | — | — | CN | disclosed |
| CN-110461833-A | 2- amino -5- oxygroup alkyl derivative and its purposes for preventing and treating undesirable plant growth | BAYER CROPSCIENCE AG | 2019-11-15 | — | — | CN | disclosed |
| CN-109329286-B | Binary Herbicidal combinations and its application comprising HPPD inhibitor class herbicide | 青岛清原化合物有限公司 | 2019-11-08 | — | — | CN | disclosed |
| CN-110392680-A | Substituted azolyl pyrrolidones and azolyl hydantoins and salts thereof and their use as herbicidal active substances | 拜耳作物科学股份公司 | 2019-10-29 | — | — | CN | disclosed |
| CN-110337436-A | Substituted 1,2,4- thiadiazolyl group pyrrolones and 1,2,4- thiadiazolyl group hydantoins and its salt and its purposes as herbicide | 拜耳作物科学股份公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-110267950-A | Substituted heteroaryl pyrrolones and its salt and its purposes as herbicidal active compounds | 拜耳作物科学股份公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110267951-A | The purposes of substituted benzyl -4-aminopyridine formic acid esters and pyrimidine -4- formic acid esters, preparation method as well as herbicide and plant growth regulator | 拜耳作物科学股份公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110087467-A | Herbicidal combination | 拜耳作物科学股份公司 | 2019-08-02 | — | — | CN | disclosed |
| US-20040077669-A1 | Pyrimidine compounds and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-04-22 | — | — | US | disclosed |
| WO-2004029204-A2 | SUBSTITUTED PYRIMIDINES | MERCK & CO., INC. (US) | 2004-04-08 | — | — | WO | disclosed |
| EP-1366026-A2 | PYRIMIDINE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002024663-A2 | PYRIMIDINE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-28 | — | — | WO | disclosed |
| CN-1326317-A | Combinations of herbicides and safeners | AVENTIS CROPSCIENCE GMBH (DE) | 2001-12-12 | — | — | CN | disclosed |
| US-5321000-A | Benzhydryl compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| US-5162537-A | To safen acetamide herbicids used to control grassy and broadleaf weeds in rice, sorghum and wheat | MONSANTO COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| US-4964893-A | REDUCING INJURY TO A CROP PLANT | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077669-A1 | Pyrimidine compounds and their use | TYMP, TYMS, DPYD | GRM5 3254/4885MAPT 3532/4885MEN1 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.