SCHEMBL3453370

SCHEMBL3453370

CC(=O)CC(C)(C)C=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14705734 0.76
SCHEMBL10683916 0.74
SCHEMBL11134540 0.72 ALDH1A1 (0.30)
SCHEMBL11134527 0.72 ALDH1A1 (0.30)
SCHEMBL11449359 0.72 ALDH1A1 (0.30)
SCHEMBL1142234 0.69 HMGCR (0.32)
SCHEMBL7470016 0.69
SCHEMBL2612030 0.67 ALDH1A1 (0.41)
SCHEMBL104505 0.67
SCHEMBL11503593 0.67 TRPA1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820866-B2 Process for the manufacture of polyphenols BADGER LICENSING LLC (US) 2010-10-26 US disclosed
US-20090137848-A1 PROCESS FOR THE MANUFACTURE OF POLYPHENOLS BADGER LICENSING LLC (US) 2009-05-28 US disclosed
EP-2021311-A1 IMPROVED PROCESS FOR THE MANUFACTURE OF POLYPHENOLS Badger Licensing LLC (US) 2009-02-11 EP disclosed
WO-2007130040-A1 IMPROVED PROCESS FOR THE MANUFACTURE OF POLYPHENOLS BADGER LICENSING LLC (US) 2007-11-15 WO disclosed
EP-1379490-A1 CATALYST PROMOTER FOR THE MANUFACTURE OF POLYPHENOLS Resolution Research Nederland B.V. (NL) 2004-01-14 EP disclosed
US-20020177740-A1 CATALYST PROMOTOR FOR THE MANUFACTURE OF POLYPHENOLS RESOLUTION PERFORMANCE PRODUCTS LLC 2002-11-28 US disclosed
WO-2002083611-A1 CATALYST PROMOTER FOR THE MANUFACTURE OF POLYPHENOLS RESOLUTION RESEARCH NEDERLAND B.V. (NL) 2002-10-24 WO disclosed
US-6465697-B1 REACTIN A PHENOLIC COMPOUND REACTANT, A CARBONYL COMPOUND REACTANT, AND A CATALYST PROMOTER COMPRISING A DITHIOKETAL COMPOUND IN THE PRESENCE OF AN ACID CATALYST. RESOLUTION PERFORMANCE PRODUCTS LLC 2002-10-15 US disclosed