Glutamic Acid

Glutamic Acid

SCHEMBL345401

N[C@@H](CCC(=O)O)C(=O)O.O=C(O)C(=O)COP(=O)(O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.56
GRM6 O15303 2/20 0.56
GRM7 Q14831 2/20 0.56
GRM4 Q14833 2/20 0.56
GRIN2D O15399 1/20 0.56
GRIN3B O60391 1/20 0.56
GSR P00390 1/20 0.56
CYP1A2 P05177 1/20 0.56
GRIK1 P39086 1/20 0.56
GRM5 P41594 1/20 0.56
GRIA1 P42261 1/20 0.56
GRIA2 P42262 1/20 0.56
GRIA3 P42263 1/20 0.56
SLC1A3 P43003 1/20 0.56
SLC1A2 P43004 1/20 0.56
SLC1A1 P43005 1/20 0.56
GRIA4 P48058 1/20 0.56
GRIN1 Q05586 1/20 0.56
GRIN2A Q12879 1/20 0.56
GRIK2 Q13002 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL15880149 0.82 GRM8 (0.62) GRM8GRM6GRM7GRM4GRIN2D
Dexfosfoserine SCHEMBL18301530 0.82 GRM8 (0.62) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL3659559 0.80 GRM8 (0.69) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL3659558 0.80 GRM8 (0.69) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL49767 0.79 GRM8 (0.82) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1065173 0.79 GRM8 (0.82) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL6363815 0.78 GRM8 (0.72) GRM8GRM6GRM7GRM4GRIN2D
Alpha-Ketoglutaric Acid SCHEMBL2030659 0.78 EGLN1 (0.56) FOLH1BLMKMT2A
D-Glutamate SCHEMBL29050535 0.78 GRM8 (0.72) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL29050515 0.78 GRM8 (0.72) GRM8GRM6GRM7GRM4GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230383318-A1 METHODS AND SYSTEMS FOR CHEMOAUTOTROPHIC PRODUCTION OF ORGANIC COMPOUNDS GINKGO BIOWORKS, INC. (US) 2023-11-30 US disclosed
US-11697829-B2 Chemoautotrophic cells comprising an engineered carbon fixation pathway GINKGO BIOWORKS, INC. (US) 2023-07-11 US disclosed
US-20230107986-A1 METHODS AND SYSTEMS FOR METHYLOTROPHIC PRODUCTION OF ORGANIC COMPOUNDS GINKGO BIOWORKS, INC. (US) 2023-04-06 US disclosed
US-20210010037-A1 METHODS AND SYSTEMS FOR CHEMOAUTOTROPHIC PRODUCTION OF ORGANIC COMPOUNDS GINKGO BIOWORKS, INC. (US) 2021-01-14 US disclosed
US-10801045-B2 Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway GINKGO BIOWORKS, INC. (US) 2020-10-13 US disclosed
US-20180223317-A1 METHODS AND SYSTEMS FOR CHEMOAUTOTROPHIC PRODUCTION OF ORGANIC COMPOUNDS GINKGO BIOWORKS, INC. 2018-08-09 US disclosed
US-20180216120-A1 METHODS AND SYSTEMS FOR METHYLOTROPHIC PRODUCTION OF ORGANIC COMPOUNDS GINKGO BIOWORKS, INC. 2018-08-02 US disclosed
US-9902980-B2 Methods and systems for chemoautotrophic production of organic compounds GINKGO BIOWORKS, INC. (US) 2018-02-27 US disclosed
US-20160145649-A1 Ethanol Production in Microorganisms JOULE UNLTD TECHNOLOGIES INC (US) 2016-05-26 US disclosed
US-9284579-B2 Ethanol production in microorganisms JOULE UNLIMITED TECHNOLOGIES, INC. (US) 2016-03-15 US disclosed
US-20120122193-A1 ENGINEERED CO2 FIXING MICROORGANISMS PRODUCING CARBON-BASED PRODUCTS OF INTEREST JOULE UNLIMITED TECHNOLOGIES, INC. (US) 2012-05-17 US disclosed
US-20120064622-A1 Methods and Systems for Chemoautotrophic Production of Organic Compounds GINKGO BIOWORKS (US) 2012-03-15 US disclosed
US-20120015427-A1 ETHANOL PRODUCTION IN MICROORGANISMS JOULE UNLIMITED TECHNOLOGIES, INC. (US) 2012-01-19 US disclosed
US-20110281335-A1 ETHANOL PRODUCTION IN MICROORGANISMS JOULE UNLIMITED, INC. (US) 2011-11-17 US disclosed
US-8048666-B1 Ethanol production in microorganisms JOULE UNLIMITED TECHNOLOGIES, INC. (US) 2011-11-01 US disclosed
US-20110262975-A1 ENGINEERED CO2 FIXING MICROORGANISMS PRODUCING CARBON-BASED PRODUCTS OF INTEREST c/o JOULE UNLIMITED, INC. (US) 2011-10-27 US disclosed
US-7981647-B2 Engineered CO2 fixing microorganisms producing carbon-based products of interest JOULE UNLIMITED, INC. (US) 2011-07-19 US disclosed
US-7968321-B1 Ethanol production by microorganisms JOULE UNLIMITED, INC. (US) 2011-06-28 US disclosed
US-20110151531-A1 ETHANOL PRODUCTION BY MICROORGANISMS JOULE UNLIMITED, INC. (US) 2011-06-23 US disclosed
US-20110008861-A1 Engineered CO2 Fixing Microorganisms Producing Carbon-Based Products of Interest JOULE UNLIMITED, INC. (US) 2011-01-13 US disclosed