Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.56 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.56 |
| ▸ | TPI1 | P60174 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | PEPD | P12955 | 1/20 | 0.34 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | MVD | P53602 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50365 | 0.87 | TPI1 (0.50) | OR51E2TPI1PGK1PGK2PEPD | |
| Alpha-Ketoglutaric Acid SCHEMBL28457662 | 0.80 | EGLN1 (0.78) | EGLN1MAPK1SLC13A3OR51E2LMNA | |
| SCHEMBL2030661 | 0.78 | TPI1 (0.36) | EGLN1MAPK1SLC13A3OR51E2TPI1 | |
| Glutamic Acid SCHEMBL345401 | 0.78 | GRM8 (0.56) | FOLH1BLMKMT2A | |
| Alpha-Ketoglutaric Acid SCHEMBL7057149 | 0.75 | MAPK1 (0.45) | EGLN1MAPK1SLC13A3OR51E2PGK1 | |
| Dexfosfoserine SCHEMBL439230 | 0.75 | MAPK1 (0.45) | EGLN1MAPK1SLC13A3OR51E2PGK1 | |
| Alpha-Ketoglutaric Acid SCHEMBL17127347 | 0.75 | EGLN1 (1.00) | EGLN1MAPK1SLC13A3OR51E2LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL932116 | 0.75 | EGLN1 (1.00) | EGLN1MAPK1SLC13A3OR51E2LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL3776640 | 0.75 | EGLN1 (1.00) | EGLN1MAPK1SLC13A3OR51E2LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL7400 | 0.75 | EGLN1 (1.00) | EGLN1MAPK1SLC13A3OR51E2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834773-B2 | Methods and means for metabolic engineering and improved product formation by micro-organisms | UNIVERSITEIT LEIDEN (NL) | 2017-12-05 | — | — | US | disclosed |
| US-20110143394-A1 | Methods and Means for Metabolic Engineering and Improved Product Formation by Micro-Organisms | UNIVERSITEIT LEIDEN (NL) | 2011-06-16 | — | — | US | disclosed |
| WO-2007094667-A9 | METHODS AND MEANS FOR METABOLIC ENGINEERING AND IMPROVED PRODUCT FORMATION BY MICRO-ORGANISMS | UNIV LEIDEN (NL) | 2009-01-29 | — | — | WO | disclosed |
| EP-1818398-A1 | Methods and means for metabolic engineering and improved product formation by micro-organisms | Universiteit Leiden (NL) | 2007-08-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110143394-A1 | Methods and Means for Metabolic Engineering and Improved Product Formation by Micro-Organisms | DCXR, GNPAT, GRHPR | EGLN1 4053/4885MAPK1 4652/4885SLC13A3 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.