Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.70 |
| ▸ | DRD3 | P35462 | 20/20 | 0.70 |
| ▸ | DRD2 | P14416 | 5/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966434 | 1.00 | HTR2A (0.70) | HTR2ADRD3DRD2 | |
| SCHEMBL1966912 | 0.96 | HTR2A (0.75) | HTR2ADRD3DRD2 | |
| SCHEMBL3453805 | 0.96 | HTR2A (0.75) | HTR2ADRD3DRD2 | |
| SCHEMBL3453936 | 0.93 | HTR2A (0.73) | HTR2ADRD3DRD2 | |
| SCHEMBL1970168 | 0.93 | HTR2A (0.68) | HTR2ADRD3DRD2 | |
| SCHEMBL1970612 | 0.93 | HTR2A (0.73) | HTR2ADRD3DRD2 | |
| SCHEMBL1965292 | 0.93 | HTR2A (0.68) | HTR2ADRD3DRD2 | |
| SCHEMBL1967490 | 0.90 | HTR2A (0.66) | HTR2ADRD3DRD2 | |
| SCHEMBL3453571 | 0.90 | HTR2A (0.66) | HTR2ADRD3DRD2 | |
| SCHEMBL3454089 | 0.90 | HTR2A (0.63) | HTR2ADRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334657-B1 | PIPERAZINE D3 AND 5-HT2A RECEPTOR MODULATORS | HOFFMANN LA ROCHE (CH) | 2013-03-06 | — | — | EP | claimed |
| US-7858630-B2 | D3 and 5-HT2A receptor modulators | HOFFMANN-LA ROCHE INC. (US) | 2010-12-28 | — | — | US | claimed |
| US-7820414-B2 | Xylitol dehydrogenase-inactivated and arabinose reductase-inhibited mutant of Candida tropicalis, method of producing high-yield of xylitol using the same, and xylitol produced thereby | LPBIO CO., LTD. (KR) | 2010-10-26 | — | — | US | claimed |
| US-20100075983-A1 | D3 AND 5-HT2A RECEPTOR MODULATORS | HOFFMANN-LA ROCHE, INC. | 2010-03-25 | — | — | US | claimed |
| US-20090004704-A1 | XYLITOL DEHYDROGENASE-INACTIVATED AND ARABINOSE REDUCTASE-INHIBITED MUTANT OF CANDIDA TROPICALIS, METHOD OF PRODUCING HIGH-YIELD OF XYLITOL USING THE SAME, AND XYLITOL PRODUCED THEREBY | LPBIO, CO., LTD. (KR) | 2009-01-01 | — | — | US | claimed |
| EP-2334657-B1 | PIPERAZINE D3 AND 5-HT2A RECEPTOR MODULATORS | HOFFMANN LA ROCHE (CH) | 2013-03-06 | — | — | EP | disclosed |
| EP-2334657-B1 | PIPERAZINE D3 AND 5-HT2A RECEPTOR MODULATORS | HOFFMANN LA ROCHE (CH) | 2013-03-06 | — | — | EP | disclosed |
| US-8343736-B2 | Xylitol producing microorganism introduced with arabinose metabolic pathway and production method of xylitol using the same | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-01-01 | — | — | US | disclosed |
| US-20120171739-A1 | Xylitol Producing Microorganism Introduced with Arabinose Metabolic Pathway and Production Method of Xylitol Using the Same | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-07-05 | — | — | US | disclosed |
| CN-102057866-B | Method for improving mutation breeding efficiency of jatropha curcas plants | XISHUANGBANNA TROPICAL BOTAN GARDEN CAS | 2012-05-02 | — | — | CN | disclosed |
| CN-102057866-A | Method for improving mutation breeding efficiency of jatropha curcas plants | XISHUANGBANNA TROPICAL BOTAN GARDEN CAS | 2011-05-18 | — | — | CN | disclosed |
| US-7858630-B2 | D3 and 5-HT2A receptor modulators | HOFFMANN-LA ROCHE INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-7858630-B2 | D3 and 5-HT2A receptor modulators | HOFFMANN-LA ROCHE INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-7820414-B2 | Xylitol dehydrogenase-inactivated and arabinose reductase-inhibited mutant of Candida tropicalis, method of producing high-yield of xylitol using the same, and xylitol produced thereby | LPBIO CO., LTD. (KR) | 2010-10-26 | — | — | US | disclosed |
| US-20100075983-A1 | D3 AND 5-HT2A RECEPTOR MODULATORS | HOFFMANN-LA ROCHE, INC. | 2010-03-25 | — | — | US | disclosed |
| US-20100075983-A1 | D3 AND 5-HT2A RECEPTOR MODULATORS | HOFFMANN-LA ROCHE, INC. | 2010-03-25 | — | — | US | disclosed |
| US-20100075983-A1 | D3 AND 5-HT2A RECEPTOR MODULATORS | HOFFMANN-LA ROCHE, INC. | 2010-03-25 | — | — | US | disclosed |
| WO-2010031735-A1 | PIPERAZINE D3 AND 5-HT2A RECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-25 | — | — | WO | disclosed |
| US-20090004704-A1 | XYLITOL DEHYDROGENASE-INACTIVATED AND ARABINOSE REDUCTASE-INHIBITED MUTANT OF CANDIDA TROPICALIS, METHOD OF PRODUCING HIGH-YIELD OF XYLITOL USING THE SAME, AND XYLITOL PRODUCED THEREBY | LPBIO, CO., LTD. (KR) | 2009-01-01 | — | — | US | disclosed |
| WO-2002048234-A2 | EPOXY RESINS AND PROCESS FOR MAKING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075983-A1 | D3 AND 5-HT2A RECEPTOR MODULATORS | HTR2A, HTR3A, HTR1A | HTR2A 1/4885DRD3 9/4885DRD2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.