SCHEMBL3454263

SCHEMBL3454263

CCCOC(=O)c1cc(O)ccc1O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.75
CA1 P00915 5/20 0.75
CA2 P00918 5/20 0.75
CA7 P43166 5/20 0.75
CA9 Q16790 5/20 0.75
CA14 Q9ULX7 5/20 0.75
ALDH1A1 P00352 2/20 0.59
ESR1 P03372 2/20 0.59
TSHR P16473 2/20 0.59
CHRM1 P11229 1/20 0.59
SLC6A2 P23975 1/20 0.59
KDR P35968 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
SERPINE1 P05121 1/20 0.59
KDM4E B2RXH2 1/20 0.53
POLB P06746 1/20 0.53
EGFR P00533 3/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ALOX5 P09917 1/20 0.48
PTGS2 P35354 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3063884 0.90 CA12 (0.71) CA12CA1CA2CA7CA9
SCHEMBL30456970 0.90 CA12 (0.71) CA12CA1CA2CA7CA9
SCHEMBL13286843 0.89 CA12 (0.73) CA12CA1CA2CA7CA9
SCHEMBL4594973 0.89 CA12 (0.69) CA12CA1CA2CA7CA9
SCHEMBL10569979 0.88 ALDH1A1 (0.65) CA12CA1CA2CA7CA9
SCHEMBL17107306 0.87 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL13422476 0.87 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL10581365 0.87 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL495935 0.87 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL31125314 0.87 CA12 (0.67) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119843294-A Preparation method of axial chiral biaryl diphenol derivative 江苏信和生物医药有限公司 2025-04-18 CN disclosed
EP-2222755-B1 LAYER CONFIGURATION WITH IMPROVED STABILITY TO SUNLIGHT EXPOSURE AGFA GEVAERT NV (BE) 2016-10-05 EP disclosed
EP-2079792-B1 LAYER CONFIGURATION WITH IMPROVED STABILITY TO SUNLIGHT EXPOSURE AGFA GEVAERT NV (BE) 2015-08-05 EP disclosed
CN-102958361-A Herbicidal compositions BASF SE 2013-03-06 CN disclosed
US-7820078-B2 Layer configuration with improved stability to sunlight exposure AGFA GRAPHICS, N.V. (BE) 2010-10-26 US disclosed
US-7670505-B2 Compounds comprising 2,6-naphthyl groups BASF AKTIENGESELLSCHAFT (DE) 2010-03-02 US disclosed
US-7670505-B2 Compounds comprising 2,6-naphthyl groups BASF AKTIENGESELLSCHAFT (DE) 2010-03-02 US disclosed
US-20090148722-A1 LAYER CONFIGURATION WITH IMPROVED STABILITY TO SUNLIGHT EXPOSURE AGFA-GEVAERT (BE) 2009-06-11 US disclosed
US-20080290324-A1 LAYER CONFIGURATION WITH IMPROVED STABILITY TO SUNLIGHT EXPOSURE AGFA-GEVAERT N.V. (BE) 2008-11-27 US disclosed
US-20080221289-A1 Compounds Comprising 2,6-Naphthyl Groups BASF AKTIENGESELLSCHAFT (DE) 2008-09-11 US disclosed
US-20080221289-A1 Compounds Comprising 2,6-Naphthyl Groups BASF AKTIENGESELLSCHAFT (DE) 2008-09-11 US disclosed
WO-2003075882-A2 METHOD OF DEPIGMENTING SKIN AND HAIRS GHISALBERTI CARLO (BR) 2003-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221289-A1 Compounds Comprising 2,6-Naphthyl Groups SCO2, MT-CO1, CBR1 CA12 581/4885CA1 512/4885CA2 810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.