Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | TP53 | P04637 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | UTRN | P46939 | 6/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454300 | 0.87 | MAOA (0.68) | MAPTTP53KDM4EALDH1A1RAB9A | |
| SCHEMBL2739327 | 0.85 | MAPT (0.76) | MAPTTP53KDM4EALDH1A1RAB9A | |
| SCHEMBL12327016 | 0.83 | RAB9A (0.64) | MAPTTP53KDM4EALDH1A1RAB9A | |
| SCHEMBL3454306 | 0.82 | MAPT (0.56) | MAPTTP53KDM4EALDH1A1RAB9A | |
| Flunoxaprofen SCHEMBL2728776 | 0.81 | MAOA (0.70) | MAPTTP53KDM4EALDH1A1RAB9A | |
| Flunoxaprofen SCHEMBL29612240 | 0.81 | MAOA (0.78) | MAPTTP53KDM4EALDH1A1RAB9A | |
| SCHEMBL12608957 | 0.81 | MAOA (0.67) | MAPTTP53KDM4EALDH1A1RAB9A | |
| Flunoxaprofen SCHEMBL25195 | 0.81 | MAOA (0.78) | MAPTTP53KDM4EALDH1A1RAB9A | |
| Flunoxaprofen SCHEMBL25196 | 0.81 | MAOA (0.78) | MAPTTP53KDM4EALDH1A1RAB9A | |
| SCHEMBL13937241 | 0.81 | KDM4E (0.58) | MAPTTP53KDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124371-A9 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2010-12-02 | — | — | WO | claimed |
| WO-2009124371-A2 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2009-10-15 | — | — | WO | claimed |