Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454459 | 0.89 | SCD (0.55) | SCD | |
| SCHEMBL3454120 | 0.89 | MAPT (0.47) | SCD | |
| SCHEMBL12464577 | 0.88 | SCD (0.51) | SCD | |
| SCHEMBL3455026 | 0.88 | PPARA (0.55) | — | |
| SCHEMBL3455194 | 0.88 | SCD (0.56) | SCD | |
| SCHEMBL3454860 | 0.87 | MAOB (0.52) | SCD | |
| SCHEMBL3454883 | 0.87 | NPC1 (0.48) | — | |
| SCHEMBL3446953 | 0.85 | CHRM4 (0.50) | — | |
| SCHEMBL3455193 | 0.84 | ATM (0.46) | SCD | |
| SCHEMBL12464767 | 0.83 | HPGD (0.67) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035052-A1 | TISSUE SELECTIVE STEAROYL-COA DESATURASE 1 INHIBITORS AND CELL BASED SCREENING ASSAY FOR THEIR IDENTIFICATION | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |