Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 5/20 | 0.55 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468898 | 0.89 | PPARA (0.52) | SCDPPARAMAPTTP53RXFP1 | |
| SCHEMBL3447237 | 0.89 | SCD (0.56) | SCDPPARAMAPTTP53LMNA | |
| SCHEMBL3454348 | 0.89 | SCD (0.55) | SCD | |
| SCHEMBL3455026 | 0.88 | PPARA (0.55) | PPARAMAPTRXFP1CHRM4SMN1; SMN2 | |
| SCHEMBL3455855 | 0.87 | PPARA (0.55) | SCDPPARAMAPTTP53RXFP1 | |
| SCHEMBL3455579 | 0.85 | MAOB (0.46) | SCDPPARAMAPTMAOBTP53 | |
| SCHEMBL13541868 | 0.84 | PPARA (0.69) | SCDPPARAMAPTMAOBPPARG | |
| SCHEMBL3455193 | 0.84 | ATM (0.46) | SCDMAOBTP53CHRM4HTT | |
| SCHEMBL3454972 | 0.83 | MAOB (0.44) | SCDPPARAMAPTMAOBTP53 | |
| SCHEMBL3454764 | 0.83 | SCD (0.44) | SCDPPARAMAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |