Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | GCGR | P47871 | 7/20 | 0.45 |
| ▸ | GIPR | P48546 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3452254 | 0.99 | PPARD (0.45) | PPARDGCGRGIPRMEN1KMT2A | |
| SCHEMBL3452179 | 0.88 | GCGR (0.44) | PPARDGCGRGIPRMEN1KMT2A | |
| SCHEMBL13109421 | 0.88 | ALDH1A1 (0.52) | PPARDMEN1KMT2AL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3452662 | 0.87 | ALDH1A1 (0.51) | PPARDMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3452661 | 0.87 | TSHR (0.52) | PPARDGCGRGIPRMEN1KMT2A | |
| SCHEMBL13109459 | 0.86 | PPARD (0.48) | PPARDGCGRGIPRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3452232 | 0.85 | PPARD (0.47) | PPARDGCGRGIPRMEN1KMT2A | |
| SCHEMBL13109431 | 0.85 | LMNA (0.55) | PPARDGCGRGIPRMEN1KMT2A | |
| SCHEMBL13109432 | 0.85 | GCGR (0.51) | PPARDGCGRGIPRMEN1KMT2A | |
| SCHEMBL13109456 | 0.84 | GCGR (0.54) | GCGRGIPRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | claimed |
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |