Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL520852 | 0.81 | SMN1; SMN2 (0.44) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL521887 | 0.74 | TSHR (0.45) | KMT2AMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL522589 | 0.73 | ALDH1A1 (0.47) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL521563 | 0.73 | ALDH1A1 (0.44) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL521703 | 0.71 | RAB9A (0.54) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL6612124 | 0.70 | MAPT (0.39) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL18625798 | 0.66 | ALDH1A1 (0.34) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL10033894 | 0.65 | KMT2A (0.39) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL27997934 | 0.65 | TAAR1 (0.71) | TAAR1ALDH1A1HPGD | |
| SCHEMBL14986110 | 0.64 | MEN1 (0.35) | KMT2AMAPTMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2196456-A1 | A method for preparing sulfur-containing compounds | Royal College of Surgeons in Ireland (IE) | 2010-06-16 | — | — | EP | disclosed |