Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5403801 | 0.84 | HDAC8 (0.41) | HDAC8KDM4EBCL2MEN1NPC1 | |
| SCHEMBL29399791 | 0.84 | — | — | |
| SCHEMBL1325535 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL1678456 | 0.82 | HDAC8 (0.48) | HDAC8KDM4EBCL2MEN1NPC1 | |
| SCHEMBL3455039 | 0.81 | HDAC8 (0.38) | HDAC8KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL29475405 | 0.77 | HDAC8 (0.43) | HDAC8KDM4EBCL2MEN1NPC1 | |
| SCHEMBL29387158 | 0.77 | HDAC8 (0.43) | HDAC8KDM4EBCL2MEN1NPC1 | |
| SCHEMBL120909 | 0.77 | HDAC8 (0.43) | HDAC8KDM4EBCL2MEN1NPC1 | |
| SCHEMBL30054627 | 0.75 | HDAC8 (0.42) | HDAC8KDM4EBCL2MEN1NPC1 | |
| SCHEMBL6681014 | 0.75 | HDAC8 (0.38) | HDAC8KDM4EMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895652-B2 | High refractive index materials and composites | AJJER, LLC (US) | 2014-11-25 | — | — | US | disclosed |
| US-20100291374-A1 | Composites Comprising Nanoparticles | AJJER LLC (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100044640-A1 | High refractive index materials and composites | AJJER LLC (US) | 2010-02-25 | — | — | US | disclosed |