Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1325535 | 0.88 | — | — | |
| SCHEMBL29399791 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL1678456 | 0.86 | HDAC8 (0.48) | HDAC8BCL2KDM4ENPC1RAB9A | |
| SCHEMBL120909 | 0.85 | HDAC8 (0.43) | HDAC8BCL2KDM4ENPC1RAB9A | |
| SCHEMBL29387158 | 0.85 | HDAC8 (0.43) | HDAC8BCL2KDM4ENPC1RAB9A | |
| SCHEMBL3455043 | 0.84 | HDAC8 (0.37) | HDAC8BCL2KDM4ENPC1RAB9A | |
| SCHEMBL30054627 | 0.83 | HDAC8 (0.42) | HDAC8BCL2KDM4ENPC1RAB9A | |
| SCHEMBL29475405 | 0.81 | HDAC8 (0.43) | HDAC8BCL2KDM4ENPC1RAB9A | |
| SCHEMBL5063458 | 0.79 | KDM4E (0.35) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6681014 | 0.79 | HDAC8 (0.38) | HDAC8KDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | claimed |
| US-7214801-B2 | Condensation reagents and a process for their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2007-05-08 | — | — | US | disclosed |
| US-20050267174-A1 | Condensation reagents and a process for their preparation | RUDOLPH JOACHIM | 2005-12-01 | — | — | US | disclosed |
| US-20020156287-A1 | Condensation reagents and a process for their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267174-A1 | Condensation reagents and a process for their preparation | C9, QPCT, RCC1 | HDAC8 4461/4885BCL2 3393/4885KDM4E 3616/4885 |
| US-20020156287-A1 | Condensation reagents and a process for their preparation | RCC1, C9, CCNT1 | HDAC8 4387/4885BCL2 3280/4885KDM4E 4040/4885 |
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | CD4, DCLRE1A, TOP1 | HDAC8 4284/4885BCL2 1897/4885KDM4E 4137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.