Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.49 |
| ▸ | ITGAV | P06756 | 13/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526495 | 1.00 | ITGB3 (0.49) | ITGB3ITGAVITGA2BBRD4CREBBP | |
| SCHEMBL8503077 | 0.86 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL8187415 | 0.84 | ITGB3 (0.49) | ITGB3ITGAVITGA2B | |
| SCHEMBL8525346 | 0.83 | ITGB3 (0.48) | ITGB3ITGAVITGA2B | |
| SCHEMBL7909994 | 0.83 | BRD4 (0.49) | ITGB3ITGAVITGA2BBRD4 | |
| SCHEMBL7919360 | 0.83 | ITGB3 (0.48) | ITGB3ITGAVITGA2B | |
| SCHEMBL4024909 | 0.82 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL4023860 | 0.82 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL5155928 | 0.82 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL7366349 | 0.81 | ITGB3 (0.58) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2196458-A1 | Process for obtaining enantiomerically enriched pyrazole derivatives | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2010-06-16 | — | — | EP | disclosed |
| US-6225465-B1 | REACTING BENZOAZEPINE OR BENZODIAZEPINE DERIVATIVE WITH PROTECTED AMINE IN PRESENCE OF PALLADIUM CATALYST IN PRESENCE OF CARBON MONOXIDE, REMOVING PROTECTING GROUPS | SMITHKLINE BEECHAM PLC (GB) | 2001-05-01 | — | — | US | disclosed |
| WO-2000063186-A1 | PROCESS AND INTERMEDIATES FOR PREPARING BENZODIAZEPINES | SMITHKLINE BEECHAM PLC (GB) | 2000-10-26 | — | — | WO | disclosed |
| EP-1019383-A2 | PROCESS FOR THE AMINOCARBONYLATION OF BENZAZEPINES AND BENZODIAZEPINES | SMITHKLINE BEECHAM PLC (GB) | 2000-07-19 | — | — | EP | disclosed |
| EP-0964928-A1 | ENZYMATIC RESOLUTION OF BENZODIAZEPINE-ACETIC ACID ESTERS WITH A LIPASE | SMITHKLINE BEECHAM PLC (GB) | 1999-12-22 | — | — | EP | disclosed |
| WO-1998029561-A1 | ENZYMATIC RESOLUTION OF BENZODIAZEPINE-ACETIC ACID ESTERS WITH A LIPASE | SMITHKLINE BEECHAM PLC (GB) | 1998-07-09 | — | — | WO | disclosed |
| WO-1997024336-A2 | PROCESS FOR THE AMINOCARBONYLATION OF BENZAZEPINES AND BENZODIAZEPINES | SMITHKLINE BEECHAM PLC (GB) | 1997-07-10 | — | — | WO | disclosed |