Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.48 |
| ▸ | ITGAV | P06756 | 15/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525346 | 1.00 | ITGB3 (0.48) | ITGB3ITGAVITGA2B | |
| SCHEMBL8187415 | 0.87 | ITGB3 (0.49) | ITGB3ITGAVITGA2B | |
| SCHEMBL8503323 | 0.87 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL7909994 | 0.86 | BRD4 (0.49) | ITGB3ITGAVITGA2B | |
| SCHEMBL5155928 | 0.85 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL4023860 | 0.85 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL4024909 | 0.85 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL8526495 | 0.83 | ITGB3 (0.49) | ITGB3ITGAVITGA2B | |
| SCHEMBL3455376 | 0.83 | ITGB3 (0.49) | ITGB3ITGAVITGA2B | |
| SCHEMBL7917615 | 0.79 | ITGB3 (0.41) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225465-B1 | REACTING BENZOAZEPINE OR BENZODIAZEPINE DERIVATIVE WITH PROTECTED AMINE IN PRESENCE OF PALLADIUM CATALYST IN PRESENCE OF CARBON MONOXIDE, REMOVING PROTECTING GROUPS | SMITHKLINE BEECHAM PLC (GB) | 2001-05-01 | — | — | US | disclosed |
| EP-1019383-A2 | PROCESS FOR THE AMINOCARBONYLATION OF BENZAZEPINES AND BENZODIAZEPINES | SMITHKLINE BEECHAM PLC (GB) | 2000-07-19 | — | — | EP | disclosed |
| WO-1997024336-A2 | PROCESS FOR THE AMINOCARBONYLATION OF BENZAZEPINES AND BENZODIAZEPINES | SMITHKLINE BEECHAM PLC (GB) | 1997-07-10 | — | — | WO | disclosed |