Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424168 | 0.86 | PPARD (0.42) | L3MBTL1PPARDKDM4EPOLBRAB9A | |
| SCHEMBL423594 | 0.83 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL19868461 | 0.71 | KDM4E (0.41) | L3MBTL1PPARDKDM4EPOLBRAB9A | |
| SCHEMBL2646780 | 0.70 | PPARD (0.42) | L3MBTL1ALDH1A1PPARDKDM4ELMNA | |
| SCHEMBL1657082 | 0.68 | KDM4E (0.41) | L3MBTL1ALDH1A1PPARDKDM4ELMNA | |
| SCHEMBL11240410 | 0.68 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL7920850 | 0.67 | KDM4E (0.43) | L3MBTL1ALDH1A1KDM4ERAB9AKMT2A | |
| SCHEMBL18128057 | 0.66 | GBA1 (0.34) | L3MBTL1ALDH1A1KDM4EPKMPOLB | |
| SCHEMBL2704697 | 0.64 | CA1 (0.61) | L3MBTL1KDM4EPOLB | |
| SCHEMBL28456854 | 0.63 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1KDM4EPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239253-A1 | NOVEL PHENYLPYRROLE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-10-13 | — | — | EP | disclosed |