Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952262 | 0.92 | MAPK1 (0.61) | MAPK1KDM4EL3MBTL1LCKGABRP | |
| SCHEMBL364090 | 0.92 | MAPK1 (0.61) | MAPK1KDM4EL3MBTL1LCKGABRP | |
| SCHEMBL25087412 | 0.81 | GABRG2 (0.44) | MAPK1KDM4EL3MBTL1GABRPGABRD | |
| SCHEMBL14740520 | 0.78 | MAPK1 (0.44) | MAPK1KDM4EL3MBTL1ALDH1A1PARP1 | |
| SCHEMBL17212397 | 0.73 | ALDH1A1 (0.44) | MAPK1KDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL29948107 | 0.73 | P4HTM (0.57) | MAPK1KDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL3719519 | 0.73 | P4HTM (0.57) | MAPK1KDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL29586464 | 0.72 | PIP5K1C (0.41) | MAPK1KDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL1397745 | 0.72 | MAPK1 (0.61) | MAPK1KDM4EL3MBTL1LCKGABRP | |
| SCHEMBL15465986 | 0.72 | PIP5K1C (0.41) | MAPK1KDM4EL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059838-A2 | PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |