Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931146 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL826755 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL7911543 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL826376 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL826329 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL2702010 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL16487196 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL22276615 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL22276602 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL8002115 | 1.00 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1915 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250352656-A1 | SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS | PEPTOMER THERAPEUTICS PRIVATE LTD (IN) | 2025-11-20 | — | — | US | claimed |
| CN-119912435-A | Nanoparticle for treating pulmonary diseases and preparation method and application thereof | 北京师范大学 | 2025-05-02 | — | — | CN | claimed |
| EP-4525827-A1 | SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS | Peptomer Therapeutics Private Limited (IN) | 2025-03-26 | — | — | EP | claimed |
| CN-118987237-A | Amphiphilic functional nano-composite and preparation method and application thereof | 河南中医药大学 | 2024-11-22 | — | — | CN | claimed |
| CN-118619952-A | Aloperine derivative, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-09-10 | — | — | CN | claimed |
| US-20240285575-A1 | NANOPARTICLES WITH ANTI-INFLAMMATORY PROPERTIES AND ENHANCED PENETRATION ACROSS THE BIOLOGICAL BARRIERS TO DELIVER ENCAPSULATED DRUGS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA | 2024-08-29 | — | — | US | claimed |
| CN-118206612-A | Ocotill type sapogenin A cycloaminothiazole ring derivative and preparation method and application thereof | 烟台大学 | 2024-06-18 | — | — | CN | claimed |
| CN-117801041-A | Preparation method and application of coumarin derivative labeled nucleoside triphosphate | 广州安必平医药科技股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117362387-A | Benzenesulfonamide piperazinone glycine derivative as well as preparation method and application thereof | 山东大学 | 2024-01-09 | — | — | CN | claimed |
| CN-117264925-A | Modified enzymes | 牛津纳米孔科技公开有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-106349335-A | Targeting antitumor drug and synthesizing method thereof | 北京化工大学 | 2017-01-25 | — | — | CN | claimed |
| US-20120178783-A1 | HDAC INHIBITORS | LIXTE BIOTECHNOLOGY, INC. | 2012-07-12 | — | — | US | claimed |
| US-8143445-B2 | HDAC inhibitors | LIXTE BIOTECHNOLOGY, INC. (US) | 2012-03-27 | — | — | US | claimed |
| EP-2200439-A1 | HDAC INHIBITORS | Lixte Biotechnology, Inc. (US) | 2010-06-30 | — | — | EP | claimed |
| US-20090143445-A1 | HDAC Inhibitors | JOHN P. WHITE, ESQ | 2009-06-04 | — | — | US | claimed |
| WO-2009045440-A1 | HDAC INHIBITORS | LIXTE BIOTECHNOLOGY HOLDINGS, INC. (US) | 2009-04-09 | — | — | WO | claimed |
| US-20050049306-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER DAVID SCOTT (US) | 2005-03-03 | — | — | US | claimed |
| US-20040010046-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2004-01-15 | — | — | US | claimed |
| US-20020110530-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER DAVID SCOTT (US) | 2002-08-15 | — | — | US | claimed |
| US-6004823-A | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-12-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178783-A1 | HDAC INHIBITORS | HDAC3, HDAC4, HDAC7 | TDP1 3530/4885MEN1 2353/4885GAA 4142/4885 |
| US-20250352656-A1 | SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS | NOD2, NGLY1, CGAS | TDP1 1294/4885MEN1 583/4885GAA 341/4885 |
| US-20050049306-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | NPM1, NOC2L, NAF1 | TDP1 3744/4885MEN1 2321/4885GAA 1523/4885 |
| US-20040010046-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | NPM1, NOC2L, NAF1 | TDP1 3744/4885MEN1 2321/4885GAA 1523/4885 |
| US-20090143445-A1 | HDAC Inhibitors | HDAC3, HDAC7, HDAC4 | TDP1 3480/4885MEN1 2360/4885GAA 4109/4885 |
| US-20020110530-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | NPM1, NOC2L, NAF1 | TDP1 3744/4885MEN1 2321/4885GAA 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.