SCHEMBL3455863

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3455140	0.90	PIM1 (0.44)	KARS1ADORA2AADORA1ADORA2BALDH1A1
	SCHEMBL3455078	0.89	ADORA2A (0.42)	ADORA2AADORA1ADORA2BADORA3PTPN7
	SCHEMBL3455656	0.88	HRH3 (0.46)	KARS1ADORA2AADORA1KDRCDK1
	SCHEMBL3456373	0.87	TLR8 (0.47)	ADORA2AADORA1KDRCDK1MAPK14
	SCHEMBL3455246	0.87	HRH3 (0.42)	KARS1ADORA2AADORA1KDRCDK1
	SCHEMBL3455793	0.86	ADORA2A (0.43)	ADORA2AADORA1ADORA2BADORA3
	SCHEMBL3455266	0.83	ADORA2A (0.47)	ADORA2AADORA1MAPK14ADORA2BADORA3
	SCHEMBL13942285	0.82	ADORA2A (0.46)	ADORA2AADORA1MAPK14ADORA2BMEN1
	SCHEMBL3455897	0.79	ADORA1 (0.45)	ADORA2AADORA1ADORA2B
	SCHEMBL3455101	0.79	ADORA2A (0.46)	ADORA2AADORA1MAPK14ADORA2BADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.