SCHEMBL3455983

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3455571	0.89	ADORA2A (0.56)	ADORA2AADORA1ADORA2BMAPTADORA3
	SCHEMBL3455115	0.89	ADORA1 (0.55)	ADORA2AADORA1ADORA2BADORA3TDP1
	SCHEMBL3457651	0.87	ADORA2A (0.61)	ADORA2AADORA1ADORA2BADORA3
	SCHEMBL13942443	0.87	ADORA2A (0.54)	ADORA2AADORA1ADORA2BADORA3
	SCHEMBL3455080	0.85	ADORA2A (0.61)	ADORA2AADORA1ADORA2BADORA3
	SCHEMBL3456812	0.84	ADORA2A (0.57)	ADORA2AADORA1ADORA2BCDC7EEF2K
	SCHEMBL27608074	0.83	ADORA2A (0.56)	ADORA2AADORA1ADORA2BADORA3
	SCHEMBL3456988	0.83	ADORA2A (0.56)	ADORA2AADORA1ADORA2BGAAADORA3
	SCHEMBL3455935	0.83	ADORA2A (0.49)	ADORA2AADORA1ADORA2BMAPTADORA3
	SCHEMBL3455329	0.83	ADORA2A (0.58)	ADORA2AADORA1ADORA2BADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.