Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36135 | 0.82 | SLC29A1 (0.41) | NT5ESLC29A1TYMP | |
| SCHEMBL34796 | 0.77 | TYMP (0.49) | NT5EHPGDTYMP | |
| SCHEMBL36555 | 0.74 | SLC29A1 (0.48) | NT5ESLC29A1TYMP | |
| SCHEMBL20769890 | 0.71 | SLC29A1 (0.71) | SLC29A1LMNARAB9ACYP3A4PKM | |
| SCHEMBL20691302 | 0.70 | SLC29A1 (0.64) | NT5ESLC29A1LMNARAB9ACYP3A4 | |
| SCHEMBL31160245 | 0.70 | SLC29A1 (0.64) | SLC29A1LMNARAB9ACYP3A4PKM | |
| SCHEMBL8595980 | 0.69 | SLC29A1 (0.59) | SLC29A1LMNARAB9ACYP3A4PKM | |
| SCHEMBL16188785 | 0.69 | TYMP (0.51) | NT5ETYMP | |
| SCHEMBL20692028 | 0.69 | SLC29A1 (0.47) | SLC29A1LMNARAB9ACYP3A4PKM | |
| SCHEMBL22349178 | 0.68 | LMNA (0.54) | NT5ESLC29A1LMNARAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210187133-A1 | Compounds and Methods of Making Compounds | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2021-06-24 | — | — | US | disclosed |
| US-20150118157-A1 | Compounds and Methods of Making Compounds | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2015-04-30 | — | — | US | disclosed |
| US-9011817-B2 | Compounds and methods of making compounds | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-04-21 | — | — | US | disclosed |
| US-20110059014-A1 | COMPOUNDS AND METHODS OF MAKING COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150118157-A1 | Compounds and Methods of Making Compounds | MCL1, TOP2B, TOP1 | NT5E 3197/4885SLC29A1 766/4885LMNA 1865/4885 |
| US-20210187133-A1 | Compounds and Methods of Making Compounds | MCL1, TOP1, TOP2B | NT5E 3428/4885SLC29A1 793/4885LMNA 1865/4885 |
| US-20110059014-A1 | COMPOUNDS AND METHODS OF MAKING COMPOUNDS | MCL1, TOP2B, TOP1 | NT5E 3197/4885SLC29A1 766/4885LMNA 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.