Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.66 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.65 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456311 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL28548697 | 0.91 | MEN1 (0.82) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL30173920 | 0.88 | MEN1 (0.79) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL30173806 | 0.88 | MEN1 (0.79) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL28551638 | 0.88 | MEN1 (0.79) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL28546977 | 0.88 | MEN1 (0.79) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL28555356 | 0.87 | MEN1 (0.77) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL28552501 | 0.87 | MEN1 (0.77) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL30173875 | 0.87 | MEN1 (0.77) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL28358398 | 0.86 | MEN1 (0.74) | MEN1KMT2AMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679470-B | (E) -1-phenyl-4-alkenyl-1H-pyrazole compound and medical application thereof | 中国药科大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-112679470-A | (E) -1-phenyl-4-alkenyl-1H-pyrazole compound and medical application thereof | 中国药科大学 | 2021-04-20 | — | — | CN | disclosed |
| US-20100179203-A1 | NOVEL PYRAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-07-15 | — | — | US | disclosed |
| EP-2176228-A1 | NOVEL PYRAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009003921-A1 | NOVEL PYRAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2009-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179203-A1 | NOVEL PYRAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | KCNN3, KCNJ2, KCNK3 | MEN1 3396/4885KMT2A 1537/4885MAPT 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.