Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | HTT | P42858 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | GSK3A | P49840 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28546977 | 1.00 | MEN1 (0.79) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL28551638 | 1.00 | MEN1 (0.79) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL30173920 | 1.00 | MEN1 (0.79) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL28549042 | 0.91 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL30173897 | 0.91 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL6679221 | 0.90 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL18742319 | 0.90 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL3456310 | 0.88 | MEN1 (1.00) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL3456311 | 0.88 | MEN1 (1.00) | MEN1KMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL11244212 | 0.83 | PTGS2 (0.76) | MEN1KMT2AALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679470-B | (E) -1-phenyl-4-alkenyl-1H-pyrazole compound and medical application thereof | 中国药科大学（CN） | 2023-01-13 | — | — | CN | disclosed |