SCHEMBL345687

SCHEMBL345687

FC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.[NaH]

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3652201 0.97 LMNA (0.38) KDM4ETSHRTDP1LMNA
SCHEMBL7179975 0.97 LMNA (0.38) KDM4ETSHRTDP1LMNA
SCHEMBL5989270 0.97 KDM4E (0.39) KDM4ETSHRTDP1LMNA
SCHEMBL5990874 0.97 KDM4E (0.39) KDM4ETSHRTDP1LMNA
SCHEMBL37369 0.97 KDM4E (0.39) KDM4ETSHRTDP1LMNA
SCHEMBL6536588 0.97 KDM4E (0.39) KDM4ETSHRTDP1LMNA
SCHEMBL816970 0.93 LMNA (0.40) KDM4ETSHRTDP1LMNA
SCHEMBL506073 0.93 LMNA (0.40) KDM4ETSHRTDP1LMNA
SCHEMBL64077 0.93 LMNA (0.40) KDM4ETSHRTDP1LMNA
SCHEMBL817265 0.93 LMNA (0.40) KDM4ETSHRTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10183873-B2 Water pretreatment unit using a fluorinated liquid ADIONICS (FR) 2019-01-22 US disclosed
US-20160318771-A1 WATER PRETREATMENT UNIT USING A FLUORINATED LIQUID ADIONICS (FR) 2016-11-03 US disclosed
US-9376330-B2 Water pretreatment unit using a fluorinated liquid ADIONICS (FR) 2016-06-28 US disclosed
US-20120012529-A1 WATER PRETREATMENT UNIT USING A FLUORINATED LIQUID ADIONICS (FR) 2012-01-19 US disclosed