SCHEMBL3652201

SCHEMBL3652201

FC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.[NaH]

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
KDM4E B2RXH2 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
THRB P10828 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7179975 1.00 LMNA (0.38) LMNAKDM4ETSHRTDP1THRB
SCHEMBL817697 0.97 LMNA (0.40) LMNAKDM4ETSHRTDP1THRB
SCHEMBL506811 0.97 LMNA (0.40) LMNAKDM4ETSHRTDP1THRB
SCHEMBL815543 0.97 LMNA (0.40) LMNAKDM4ETSHRTDP1THRB
SCHEMBL506073 0.97 LMNA (0.40) LMNAKDM4ETSHRTDP1THRB
SCHEMBL716297 0.97 LMNA (0.40) LMNAKDM4ETSHRTDP1THRB
SCHEMBL735601 0.97 LMNA (0.40) LMNAKDM4ETSHRTDP1THRB
SCHEMBL817265 0.97 LMNA (0.40) LMNAKDM4ETSHRTDP1THRB
SCHEMBL64077 0.97 LMNA (0.40) LMNAKDM4ETSHRTDP1THRB
SCHEMBL816970 0.97 LMNA (0.40) LMNAKDM4ETSHRTDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283892-A Polyfluoroalkyl sultone and preparation method thereof 华中师范大学 2023-06-23 CN disclosed
CN-114539197-B Synthesis method of 3-fluoroalkyl substituted chromone derivative 浙江工业大学 2023-05-30 CN disclosed
EP-2205649-B1 PROCESS FOR PRODUCING FLUOROPOLYMERS DU PONT (US) 2012-12-26 EP disclosed
EP-2205649-A1 PROCESS FOR PRODUCING FLUOROPOLYMERS DuPont Performance Elastomers L.L.C. (US) 2010-07-14 EP disclosed
US-20090124755-A1 PROCESS FOR PRODUCING FLUOROPOLYMERS DUPONT PERFORMANCE ELASTOMERS L.L.C. 2009-05-14 US disclosed
WO-2009062006-A1 PROCESS FOR PRODUCING FLUOROPOLYMERS DUPONT PERFORMANCE ELASTOMERS L.L.C. (US) 2009-05-14 WO disclosed