SCHEMBL3456907

SCHEMBL3456907

CCCCCCCCC1(CCCCCCCC)c2cc(-c3ccccc3-c3ccncc3)ccc2-c2ccc([Si](C)(C)C)cc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 6/20 0.39
GCGR P47871 3/20 0.36
MAPK14 Q16539 1/20 0.36
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP19A1 P11511 1/20 0.32
LTB4R2 Q9NPC1 1/20 0.31
PTPN11 Q06124 1/20 0.31
MMP2 P08253 2/20 0.30
MMP9 P14780 2/20 0.30
MMP8 P22894 2/20 0.30
MMP13 P45452 2/20 0.30
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
RAB9A P51151 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3457110 0.90 PDK2 (0.42) PDK2GCGRMAPK14CYP3A4CYP2D6
SCHEMBL3456617 0.85 GCGR (0.37) PDK2GCGRMAPK14CYP3A4CYP2D6
SCHEMBL16265319 0.84 PDK2 (0.41) PDK2MMP2MMP9MMP8MMP13
SCHEMBL3457057 0.84 PDK2 (0.39) PDK2GCGRMAPK14CYP3A4CYP2D6
SCHEMBL3457852 0.83 MMP2 (0.34) PDK2CYP19A1MMP2MMP9MMP8
SCHEMBL10019514 0.82 MMP2 (0.37) PDK2MMP2MMP9MMP8MMP13
SCHEMBL25357281 0.82 MMP2 (0.41) PDK2PTPN11MMP2MMP9MMP8
SCHEMBL8405373 0.82 CYP3A4 (0.44) PDK2GCGRMAPK14CYP3A4CYP2D6
Boric Acid SCHEMBL27545426 0.80 PDK2 (0.40) PDK2MMP2MMP9MMP8MMP13
Boric Acid SCHEMBL27565252 0.80 PDK2 (0.40) PDK2MMP2MMP9MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2264123-B1 PROCESS FOR THE PREPARATION OF SOLUTION-PROCESSABLE PHOSPHORESCENT MATERIALS CAMBRIDGE ENTPR LTD (GB) 2016-12-28 EP disclosed
EP-1501907-B1 SOLUTION-PROCESSABLE PHOSPHORESCENT MATERIALS CAMBRIDGE ENTPR LTD (GB) 2016-07-27 EP disclosed
US-9023978-B2 Solution-processable phosphorescent materials CAMBRIDGE ENTERPRISE LTD. (GB) 2015-05-05 US disclosed
EP-2264123-A2 Solution-processable phosphorescent materials Cambridge Display Technology Limited (GB) 2010-12-22 EP disclosed
US-20060063026-A1 Solution-processable phosphorescent materials CAMBRIDGE ENTERPRISE LTD (GB) 2006-03-23 US disclosed
EP-1501907-A2 SOLUTION-PROCESSABLE PHOSPHORESCENT MATERIALS CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) 2005-02-02 EP disclosed
WO-2003091355-A2 SOLUTION-PROCESSABLE PHOSPHORESCENT MATERIALS CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) 2003-11-06 WO disclosed