SCHEMBL3457852

SCHEMBL3457852

CCCCCCCCC1(CCCCCCCC)c2cc([Si](C)(C)C)ccc2-c2ccc([Si](C)(C)C)cc21

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.34
MMP9 P14780 4/20 0.34
MMP8 P22894 4/20 0.34
MMP13 P45452 4/20 0.34
PDK2 Q15119 3/20 0.34
CNR1 P21554 4/20 0.33
CNR2 P34972 4/20 0.33
CYP19A1 P11511 1/20 0.30
SIRT2 Q8IXJ6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16265319 0.93 PDK2 (0.41) MMP2MMP9MMP8MMP13PDK2
SCHEMBL27567063 0.92 RAB9A (0.33) MMP2MMP9MMP8MMP13PDK2
SCHEMBL3456777 0.92 RAB9A (0.33) MMP2MMP9MMP8MMP13PDK2
SCHEMBL5498381 0.90 NPC1 (0.33) PDK2
Boric Acid SCHEMBL27565252 0.88 PDK2 (0.40) MMP2MMP9MMP8MMP13PDK2
Boric Acid SCHEMBL27545426 0.88 PDK2 (0.40) MMP2MMP9MMP8MMP13PDK2
SCHEMBL1647322 0.88 LIPG (0.38) PDK2CNR1CNR2
SCHEMBL5788364 0.88 LIPG (0.38) PDK2CNR1CNR2
SCHEMBL5503194 0.86 LPL (0.37) PDK2
SCHEMBL10019512 0.86 TSHR (0.32) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1169741-B1 POLYMERS, THEIR PREPARATION AND USES SUMITOMO CHEMICAL CO (JP) 2014-08-13 EP disclosed
EP-2267813-A1 Polymers, their preparation and uses Sumitomo Chemical Company, Limited (JP) 2010-12-29 EP disclosed
EP-2267816-A1 Polymers, their preparation and uses Sumitomo Chemical Company, Limited (JP) 2010-12-29 EP disclosed
EP-2267815-A1 Polymers, their preparation and uses Sumitomo Chemical Company, Limited (JP) 2010-12-29 EP disclosed
EP-2267814-A1 Polymers, their preparation and uses Sumitomo Chemical Company, Limited (JP) 2010-12-29 EP disclosed
EP-2262029-A2 Polymers, their preparation and uses Sumitomo Chemical Company, Limited (JP) 2010-12-15 EP disclosed
EP-2262028-A2 Polymers, their preparation and uses Sumitomo Chemical Company, Limited (JP) 2010-12-15 EP disclosed
EP-2262027-A2 Polymers, their preparation and uses Sumitomo Chemical Company, Limited (JP) 2010-12-15 EP disclosed
EP-2262026-A2 Polymers, their preparation and uses Sumitomo Chemical Company, Limited (JP) 2010-12-15 EP disclosed
US-6861502-B1 Polymers, their preparation and uses DOW GLOBAL TECHNOLOGIES INC. (US) 2005-03-01 US disclosed