Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | PLAT | P00750 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364095 | 0.79 | HSP90AA1 (0.55) | ASIC3NOS1NOS3ADORA2AAPP | |
| SCHEMBL30507528 | 0.78 | HSP90AA1 (0.53) | NCOA1NCOA3ADORA2A | |
| SCHEMBL28501185 | 0.78 | HSP90AA1 (0.53) | NCOA1NCOA3ADORA2A | |
| SCHEMBL21223169 | 0.77 | NCOA1 (0.47) | NCOA1NCOA3BRD4ADORA2APTGS2 | |
| Hydrochloric Acid SCHEMBL21223725 | 0.75 | NCOA1 (0.46) | NCOA1NCOA3BRD4ELANEADORA2A | |
| SCHEMBL2194879 | 0.74 | GRM5 (0.51) | NCOA1NCOA3PTGS2NPC1RAB9A | |
| SCHEMBL2203391 | 0.73 | TSHR (0.58) | NCOA1NCOA3BRD4DPP4PTGS2 | |
| SCHEMBL3394031 | 0.73 | NCOA1 (0.44) | NCOA1NCOA3BRD4ADORA2APTGS2 | |
| SCHEMBL3457107 | 0.72 | NCOA1 (0.54) | NCOA1NCOA3BRD4ADORA2AFYN | |
| SCHEMBL4282002 | 0.72 | HSP90AA1 (0.69) | NCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264010-A1 | Hetarylamidines | Bayer CropScience AG (DE) | 2010-12-22 | — | — | EP | disclosed |
| EP-2264010-A1 | Hetarylamidines | Bayer CropScience AG (DE) | 2010-12-22 | — | — | EP | disclosed |