SCHEMBL3457327

SCHEMBL3457327

[CH]=C1C=CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16059132 0.80
SCHEMBL1381822 0.67
SCHEMBL692915 0.67 ALDH1A1 (1.00)
SCHEMBL9892 0.67
SCHEMBL204351 0.67
SCHEMBL1143867 0.67
SCHEMBL649143 0.67
SCHEMBL8744217 0.67
SCHEMBL15351762 0.67
SCHEMBL38662853 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11999193-B2 Tyre for vehicle wheels PIRELLI TYRE S.P.A. (IT) 2024-06-04 US disclosed
US-20230045260-A1 TYRE FOR VEHICLE WHEELS PIRELLI TYRE S.P.A. (IT) 2023-02-09 US disclosed
US-11518192-B2 Tyre for vehicle wheels PIRELLI TYRE S.P.A. (IT) 2022-12-06 US disclosed
WO-2018163041-A2 TYRE FOR VEHICLE WHEELS PIRELLI TYRE S.P.A. (IT) 2018-09-13 WO disclosed
EP-2970265-B1 HETEROCYCLIC COMPOUNDS AND USES THEREOF PLEXXIKON INC (US) 2018-08-08 EP disclosed
US-20180072722-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Opna Bio SA (CH) 2018-03-15 US disclosed
US-9856259-B2 Heterocyclic compounds and uses thereof PLEXXIKON INC. (US) 2018-01-02 US disclosed
US-9822109-B2 Heterocyclic compounds and uses thereof PLEXXIKON INC. (US) 2017-11-21 US disclosed
US-20170320899-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF PLEXXIKON INC. (US) 2017-11-09 US disclosed
US-9718847-B2 Heterocyclic compounds and uses thereof PLEXXIKON INC. (US) 2017-08-01 US disclosed
US-7544814-B2 [3.2.0] Heterocyclic compounds and methods of using the same NEREUS PHARMACEUTICALS, INC. (US) 2009-06-09 US disclosed
EP-2025679-A2 [3.2.0] Heterocyclic compounds and methods of using the same Nereus Pharmaceuticals, Inc. (US) 2009-02-18 EP disclosed
US-20080070969-A1 [3.2.0] HETEROCYCLIC COMPOUNDS AND METHODS OF USING THE SAME NEREUS PHARMACEUTICALS, INC. (US) 2008-03-20 US disclosed
US-7276530-B2 [3.2.0] Heterocyclic compounds and methods of using the same NEREUS PHARMACEUTICALS, INC. (US) 2007-10-02 US disclosed
EP-1812443-A2 [3.2.0] HETEROCYCLIC COMPOUNDS AND METHODS OF USING THE SAME Nereus Pharmaceuticals, Inc. (US) 2007-08-01 EP disclosed
US-20070004676-A1 Methods of using [3.2.0] heterocyclic compounds and analogs thereof TRIPHASE RESEARCH AND DEVELOPMENT I CORP. (CA) 2007-01-04 US disclosed
WO-2006028525-A2 [3.2.0] HETEROCYCLIC COMPOUNDS AND METHODS OF USING THE SAME NEREUS PHARMACEUTICALS, INC. (US) 2006-03-16 WO disclosed
US-20050288352-A1 [3.2.0] Heterocyclic compounds and methods of using the same TRIPHASE RESEARCH AND DEVELOPMENT I CORP. (CA) 2005-12-29 US disclosed
US-4711775-A ANTIDANDRUFF HAIR LOTIONS AND SHAMPOOS HOECHST AKTIENGESELLSCHAFT (DE) 1987-12-08 US disclosed
US-4185106-A Pyridones as antidandruff agents HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-22 US disclosed