SCHEMBL692915

SCHEMBL692915

O=C1C=CCCC1.O=C1C=CCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
CA1 P00915 2/20 0.36
CA9 Q16790 2/20 0.36
KIT P10721 2/20 0.35
PDGFRA P16234 2/20 0.35
FLT1 P17948 2/20 0.35
FLT4 P35916 2/20 0.35
KDR P35968 2/20 0.35
FLT3 P36888 2/20 0.35
PDGFRB P09619 1/20 0.35
MAP2K1 Q02750 1/20 0.35
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
CDC25B P30305 1/20 0.33
BCHE P06276 1/20 0.32
POLB P06746 1/20 0.32
MAOA P21397 1/20 0.32
ACHE P22303 1/20 0.32
MAOB P27338 1/20 0.32
APEX1 P27695 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29504106 1.00
SCHEMBL9892 1.00
Water SCHEMBL28870380 0.97
SCHEMBL32889302 0.97
SCHEMBL28737096 0.97
Methane SCHEMBL767442 0.97
SCHEMBL3115003 0.97
SCHEMBL3118210 0.97
SCHEMBL3120186 0.97
Water SCHEMBL28855852 0.97 ALDH1A1 (0.94) ALDH1A1CA1CA9KITPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2205557-B1 METHOD FOR PRODUCING BETA-MERCAPTOCARBOXYLIC ACIDS SHOWA DENKO KK (JP) 2012-02-29 EP disclosed
JP-2012017301-A CYCLOHEXENONES AND METHOD OF PRODUCING THE SAME NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY 2012-01-26 JP disclosed
US-20110124919-A1 3-AMINOMETHYL-1-CYCLOHEXYLAMINE, AND METHOD FOR THE PRODUCTION THEREOF BASF SE (DE) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124919-A1 3-AMINOMETHYL-1-CYCLOHEXYLAMINE, AND METHOD FOR THE PRODUCTION THEREOF PNMT, CBR3, ALKBH3 ALDH1A1 2877/4885CA1 1518/4885CA9 2840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.