Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 7/20 | 0.44 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865789 | 0.80 | KDM4E (0.42) | TRIM24TRIM33KDM4EGAAL3MBTL1 | |
| SCHEMBL4669668 | 0.80 | KDM4E (0.42) | TRIM24TRIM33KDM4EGAAL3MBTL1 | |
| SCHEMBL4669664 | 0.80 | KDM4E (0.42) | TRIM24TRIM33KDM4EGAAL3MBTL1 | |
| SCHEMBL247861 | 0.78 | TRIM24 (0.52) | TRIM24TRIM33KDM4EGAAL3MBTL1 | |
| SCHEMBL2037793 | 0.78 | TRIM24 (0.52) | TRIM24TRIM33KDM4EGAAL3MBTL1 | |
| SCHEMBL8982379 | 0.78 | TRIM24 (0.52) | TRIM24TRIM33KDM4EGAAL3MBTL1 | |
| SCHEMBL49775 | 0.76 | TRPA1 (0.43) | TRIM24TRIM33KDM4EGAAL3MBTL1 | |
| SCHEMBL3690222 | 0.76 | MAPT (0.40) | TRIM24TRIM33KDM4EGAAL3MBTL1 | |
| SCHEMBL3690223 | 0.76 | MAPT (0.40) | TRIM24TRIM33KDM4EGAAL3MBTL1 | |
| SCHEMBL1697046 | 0.76 | TRPA1 (0.43) | TRIM24TRIM33KDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266954-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | Draximage, Inc. (CA) | 2010-12-29 | — | — | EP | disclosed |
| EP-2266953-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | Draximage, Inc. (CA) | 2010-12-29 | — | — | EP | disclosed |