Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13540671 | 0.90 | RAB9A (0.73) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL3463497 | 0.87 | NPC1 (0.81) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL27834920 | 0.85 | RAB9A (1.00) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL3462569 | 0.83 | RAB9A (0.74) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL3463191 | 0.80 | NPC1 (0.64) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL13540759 | 0.74 | NPC1 (0.60) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL28147012 | 0.74 | RAB9A (0.71) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL28844162 | 0.72 | NPC1 (0.60) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL27834924 | 0.72 | RAB9A (0.72) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL31192457 | 0.71 | NPC1 (0.62) | RAB9ANPC1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |