Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18783662 | 0.89 | MCL1 (0.54) | MCL1MAPTALDH1A1MEN1PKM | |
| SCHEMBL3457588 | 0.86 | IDO1 (0.50) | MCL1MAPTALDH1A1MEN1PKM | |
| SCHEMBL3462870 | 0.86 | MCL1 (0.46) | MCL1MAPTALDH1A1MEN1PKM | |
| SCHEMBL14774677 | 0.82 | MEN1 (0.64) | MCL1MAPTALDH1A1MEN1PKM | |
| SCHEMBL18783685 | 0.82 | MAPT (0.56) | MCL1MAPTALDH1A1MEN1PKM | |
| SCHEMBL18783716 | 0.82 | FNTA (0.52) | MCL1MAPTMEN1PKMKMT2A | |
| SCHEMBL23005041 | 0.81 | MCL1 (0.61) | MCL1MAPTALDH1A1MEN1PKM | |
| SCHEMBL14774883 | 0.80 | MEN1 (0.46) | MCL1MAPTALDH1A1MEN1PKM | |
| SCHEMBL483546 | 0.78 | MCL1 (0.61) | MCL1MAPTALDH1A1MEN1PKM | |
| SCHEMBL1577187 | 0.78 | MCL1 (0.57) | MCL1MAPTALDH1A1MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820709-B2 | N-phenylpyrazole derivatives as pesticides | MERIAL LIMITED (US) | 2010-10-26 | — | — | US | disclosed |
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |
| US-20070281987-A1 | N-phenylpyrazole derivatives as pesticides | MERIAL, INC. | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281987-A1 | N-phenylpyrazole derivatives as pesticides | ACHE, CYP3A5, PTMS | MCL1 3261/4885MAPT 1474/4885ALDH1A1 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.