Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3457659 | 0.86 | MCL1 (0.61) | MCL1MAPTALDH1A1L3MBTL1PKM | |
| SCHEMBL14774615 | 0.85 | PTGER1 (0.41) | MCL1MAPTALDH1A1L3MBTL1MEN1 | |
| SCHEMBL14774620 | 0.77 | IDO1 (0.42) | IDO1 | |
| SCHEMBL3457588 | 0.77 | IDO1 (0.50) | MCL1MAPTALDH1A1L3MBTL1PKM | |
| SCHEMBL18783662 | 0.76 | MCL1 (0.54) | MCL1MAPTALDH1A1L3MBTL1PKM | |
| SCHEMBL13154284 | 0.75 | RXRA (0.45) | MCL1MAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL561222 | 0.74 | HTR1A (0.67) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL18783716 | 0.73 | FNTA (0.52) | MCL1MAPTPKMKDM4EMEN1 | |
| SCHEMBL3304485 | 0.73 | TAAR1 (0.38) | ALDH1A1KDM4EGAALMNAHTT | |
| SCHEMBL5973961 | 0.72 | TAAR1 (0.39) | ALDH1A1L3MBTL1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |