Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.79 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.63 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.63 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29536364 | 0.89 | DHODH (1.00) | DHODHKDM4EPDE10ALMNASMN1; SMN2 | |
| SCHEMBL2467110 | 0.89 | DHODH (1.00) | DHODHKDM4EPDE10ALMNASMN1; SMN2 | |
| Cinchophen SCHEMBL7588217 | 0.89 | KDM4E (1.00) | DHODHKDM4EPDE10ALMNASMN1; SMN2 | |
| Cinchophen SCHEMBL25519 | 0.89 | KDM4E (1.00) | DHODHKDM4EPDE10ALMNASMN1; SMN2 | |
| Cinchophen SCHEMBL29376617 | 0.89 | KDM4E (1.00) | DHODHKDM4EPDE10ALMNASMN1; SMN2 | |
| SCHEMBL20414373 | 0.88 | DHODH (0.62) | DHODHKDM4EPDE10ALMNASMN1; SMN2 | |
| Cinchophen SCHEMBL10757475 | 0.87 | KDM4E (0.97) | DHODHKDM4EPDE10ALMNASMN1; SMN2 | |
| Cinchophen SCHEMBL4805149 | 0.87 | KDM4E (0.97) | DHODHKDM4EPDE10ALMNASMN1; SMN2 | |
| Cinchophen SCHEMBL4464779 | 0.87 | KDM4E (0.97) | DHODHKDM4EPDE10ALMNASMN1; SMN2 | |
| SCHEMBL8689228 | 0.86 | DHODH (0.82) | DHODHKDM4EPDE10ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096170-A2 | INHIBITION OF TRNA SYNTHETASES AND THERAPEUTIC APPLICATIONS THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-08-26 | — | — | WO | disclosed |
| US-7666813-B2 | an aliphatic amine, in particular an alkanolamine, and a non-hydroquinoid antioxidant for removal of CO2, H2S, SO2, CS2, HCN, COS, disulfides or mercaptans as impurities in reaction gases formed in the oxidation of organic materials to prevent the emission of above gases | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-23 | — | — | US | disclosed |
| US-20050202967-A1 | an aliphatic amine, in particular an alkanolamine, and a non-hydroquinoid antioxidant for removal of CO2, H2S, SO2, CS2, HCN, COS, disulfides or mercaptans as impurities in reaction gases formed in the oxidation of organic materials to prevent the emission of above gases | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-15 | — | — | US | disclosed |