Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.97 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.97 |
| ▸ | LMNA | P02545 | 1/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.97 |
| ▸ | DHODH | Q02127 | 6/20 | 0.90 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.75 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.75 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinchophen SCHEMBL25519 | 0.98 | KDM4E (1.00) | KDM4EPDE10ALMNASMN1; SMN2DHODH | |
| Cinchophen SCHEMBL29376617 | 0.98 | KDM4E (1.00) | KDM4EPDE10ALMNASMN1; SMN2DHODH | |
| Cinchophen SCHEMBL7588217 | 0.98 | KDM4E (1.00) | KDM4EPDE10ALMNASMN1; SMN2DHODH | |
| Cinchophen SCHEMBL10757475 | 0.97 | KDM4E (0.97) | KDM4EPDE10ALMNASMN1; SMN2DHODH | |
| Cinchophen SCHEMBL4464779 | 0.97 | KDM4E (0.97) | KDM4EPDE10ALMNASMN1; SMN2DHODH | |
| SCHEMBL29536364 | 0.95 | DHODH (1.00) | KDM4EPDE10ALMNASMN1; SMN2DHODH | |
| Cinchophen SCHEMBL27543969 | 0.95 | KDM4E (0.93) | KDM4EPDE10ALMNASMN1; SMN2DHODH | |
| SCHEMBL2467110 | 0.95 | DHODH (1.00) | KDM4EPDE10ALMNASMN1; SMN2DHODH | |
| SCHEMBL29359819 | 0.89 | KDM4E (0.83) | KDM4EPDE10ALMNASMN1; SMN2DHODH | |
| SCHEMBL18746 | 0.89 | KDM4E (0.83) | KDM4EPDE10ALMNASMN1; SMN2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399434-B2 | Rare metal compounds and mixtures of these | HONEYWELL INTERNATIONAL INC (US) | 2008-07-15 | — | — | US | disclosed |
| CN-1329399-C | Rare earth metal compounds and mixtures of these | HONEYWELL SPECIALTY CHEMICALS (DE) | 2007-08-01 | — | — | CN | disclosed |
| US-7198732-B2 | Rare earth metal compounds and mixtures of these | HONEYWELL INTERNATIONAL INC. (US) | 2007-04-03 | — | — | US | disclosed |
| US-20070051929-A1 | Rare metal compounds and mixtures of these | HONEYWELL INTERNATIONAL INC. (US) | 2007-03-08 | — | — | US | disclosed |
| CN-1608072-A | Rare earth metal compounds and mixtures thereof | HONEYWELL SPECIALTY CHEMICALS (DE) | 2005-04-20 | — | — | CN | disclosed |
| EP-1456213-B1 | RARE EARTH METAL COMPOUNDS AND MIXTURES OF THESE | HONEYWELL SPECIALTY CHEMICALS (DE) | 2005-03-30 | — | — | EP | disclosed |
| US-20040262575-A1 | Rare earth metal compounds and mixtures of these | POTRAWA THOMAS | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040262575-A1 | Rare earth metal compounds and mixtures of these | SOD1, ERCC4, ERCC1 | KDM4E 4140/4885PDE10A 3524/4885LMNA 1508/4885 |
| US-20070051929-A1 | Rare metal compounds and mixtures of these | RUVBL2, SOD1, MSH6 | KDM4E 3196/4885PDE10A 3160/4885LMNA 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.