Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL596325 | 0.88 | ADORA1 (0.38) | F12C5AR1NR1H2ADORA1 | |
| SCHEMBL19201023 | 0.85 | C5AR1 (0.32) | F12C5AR1JAK1 | |
| SCHEMBL6375680 | 0.84 | C5AR1 (0.35) | F12C5AR1NR1H2ADORA1 | |
| SCHEMBL16622327 | 0.78 | C5AR1 (0.37) | C5AR1NR1H2ADORA1 | |
| SCHEMBL6377226 | 0.75 | C5AR1 (0.36) | C5AR1 | |
| SCHEMBL19312086 | 0.74 | C5AR1 (0.35) | C5AR1ADORA1JAK1 | |
| SCHEMBL3327257 | 0.74 | C5AR1 (0.33) | C5AR1 | |
| SCHEMBL28839345 | 0.73 | F12 (0.35) | F12NR1H2ADORA1 | |
| SCHEMBL3331339 | 0.73 | C5AR1 (0.34) | C5AR1ADORA1 | |
| SCHEMBL28926418 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266987-A1 | Substituted pyrrolo-pyrazole derivatives as kinase inhibitors | Pfizer Italia S.r.l. (IT) | 2010-12-29 | — | — | EP | disclosed |