Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Butyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 6/20 | 0.48 |
| ▸ | CES2 | O00748 | 5/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyl Alcohol SCHEMBL65184 | 0.97 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| Butyl Alcohol SCHEMBL7102169 | 0.97 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| Butyl Alcohol SCHEMBL28258914 | 0.97 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| Butyl Alcohol SCHEMBL4329735 | 0.94 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| Butyl Alcohol SCHEMBL27685696 | 0.94 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| Butyl Alcohol SCHEMBL27615272 | 0.94 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| Butyl Alcohol SCHEMBL148760 | 0.94 | — | — | |
| Butyl Alcohol SCHEMBL27390375 | 0.94 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| Butyl Alcohol SCHEMBL15662929 | 0.92 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 | |
| Butyl Alcohol SCHEMBL10833194 | 0.92 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099155-A1 | RECOVERY OF VOLATILE PRODUCTS FROM FERMENTATION BROTH | FRANK TIMOTHY C | 2010-04-22 | — | — | US | disclosed |
| CN-101563138-A | Recovery of volatile products from fermentation broth | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-10-21 | — | — | CN | disclosed |