Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Butyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.53 |
| ▸ | PPARD known ✓ | Q03181 | 2/20 | 0.38 |
| ▸ | HDAC11 known ✓ | Q96DB2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 6/20 | 0.50 |
| ▸ | CES2 | O00748 | 5/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyl Alcohol SCHEMBL27685696 | 0.97 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Butyl Alcohol SCHEMBL3457940 | 0.97 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Butyl Alcohol SCHEMBL27615272 | 0.97 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Butyl Alcohol SCHEMBL27390375 | 0.97 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Butyl Alcohol SCHEMBL148760 | 0.97 | — | — | |
| Butyl Alcohol SCHEMBL15662929 | 0.94 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Butyl Alcohol SCHEMBL4103938 | 0.94 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Butyl Alcohol SCHEMBL352043 | 0.94 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Hexane SCHEMBL28594592 | 0.94 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Butyl Alcohol SCHEMBL27587645 | 0.94 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669604-B | A method of wildness hazel-mushroom taxol is purified using ultra high pressure extraction, biological enzymolysis, adverse current chromatogram | 大兴安岭富林山野珍品科技开发有限责任公司 | 2018-12-25 | — | — | CN | claimed |
| CN-117871716-A | Method for detecting ethyl carbamate in liquid seasoning | 湖州市食品药品检验研究院(湖州市药品和医疗器械不良反应监测中心、湖州市医疗器械监督检验中心、湖州市食品认证审评和粮油质量监测中心) | 2024-04-12 | — | — | CN | disclosed |
| CN-105669604-B | A method of wildness hazel-mushroom taxol is purified using ultra high pressure extraction, biological enzymolysis, adverse current chromatogram | 大兴安岭富林山野珍品科技开发有限责任公司 | 2018-12-25 | — | — | CN | disclosed |
| CN-107126486-A | The induction mononuclear macrophage differentiation secretion of alocasia cucullata Schott water extract plays the application of anti-tumor function | 南方医科大学 | 2017-09-05 | — | — | CN | disclosed |
| CN-105181847-B | A kind of multi information gradient thinlayer discrimination method of Sculellaria barbata medicinal material and its water extract | 河北中医学院 | 2017-06-23 | — | — | CN | disclosed |
| WO-2004000233-A2 | ALGAL GDP-MANNOSE-3',5'-EPIMERASES AND METHODS OF USE THEREOF | ARKION LIFE SCIENCES LLC (US) | 2003-12-31 | — | — | WO | disclosed |
| US-6586393-B2 | Cyclic peptide antibiotics from Actinomadura sp. of given formula; selective inhibitory activity against E. coli RNA polymerase; use treating infections | BIOSEARCH ITALIA S.P.A. (IT) | 2003-07-01 | — | — | US | disclosed |
| US-20020115597-A1 | Antibiotics GE 23077, pharmaceutically acceptable salts and compositions, and use thereof | BIOSEARCH ITALIA S.P.A. (IT) | 2002-08-22 | — | — | US | disclosed |
| EP-1213298-A1 | Antibiotics GE 23077, pharmaceutically acceptable salts and compositions, and use thereof | Biosearch Italia S.p.A. (IT) | 2002-06-12 | — | — | EP | disclosed |
| US-5122450-A | Reaction product of oligosaccharide and lipid spacer molecule on immobilized carrier; reactive aldehyde and amine groups; phosphatides; neoglycolipids; testing kits | RESEARCH CORPORATION LIMITED (GB) | 1992-06-16 | — | — | US | disclosed |
| WO-1992003565-A1 | OLIGOSACCHARIDE MIXTURE, AND PROCEDURE FOR ITS MANUFACTURING | OY ALKO AB (FI) | 1992-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115597-A1 | Antibiotics GE 23077, pharmaceutically acceptable salts and compositions, and use thereof | MRPS27, RPS27, RPS27L | MEN1 3465/4885PPARD 1159/4885HDAC11 2256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.