Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.55 |
| ▸ | CNR2 | P34972 | 4/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4831202 | 0.83 | SMN1; SMN2 (0.58) | MGLLCNR2TRPV1CNR1HTR1A | |
| SCHEMBL4404110 | 0.83 | TRPV1 (0.59) | MGLLCNR2TRPV1CNR1HTR1A | |
| SCHEMBL4825891 | 0.77 | ALDH1A1 (0.46) | CNR2TRPV1CNR1HTR1AHTR2C | |
| SCHEMBL2644386 | 0.74 | SMN1; SMN2 (0.69) | TRPM8SMN1; SMN2NPC1PKMRAB9A | |
| SCHEMBL23277296 | 0.72 | — | — | |
| SCHEMBL4407827 | 0.70 | CNR2 (0.56) | MGLLCNR2TRPV1CNR1HDAC6 | |
| SCHEMBL4412024 | 0.69 | — | — | |
| SCHEMBL22187173 | 0.69 | CNR2 (0.63) | MGLLCNR2TRPV1CNR1HDAC6 | |
| SCHEMBL4405605 | 0.67 | HDAC6 (0.68) | MGLLCNR2TRPV1CNR1HDAC6 | |
| SCHEMBL4407064 | 0.67 | CNR2 (0.52) | MGLLCNR2TRPV1CNR1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018438-A2 | TETRAZOLE GLYCOSIDES | HETERO RESEARCH FOUNDATION (IN) | 2010-02-18 | — | — | WO | disclosed |
| WO-2010018438-A2 | TETRAZOLE GLYCOSIDES | HETERO RESEARCH FOUNDATION (IN) | 2010-02-18 | — | — | WO | disclosed |