Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 5/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458046 | 0.83 | MGLL (0.55) | SMN1; SMN2LMNACNR2TRPV1CNR1 | |
| SCHEMBL4404110 | 0.83 | TRPV1 (0.59) | SMN1; SMN2LMNACNR2TRPV1CNR1 | |
| SCHEMBL4825854 | 0.79 | CYP3A4 (0.45) | SMN1; SMN2LMNACNR2TRPV1CNR1 | |
| SCHEMBL4825891 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2CNR2TRPV1CNR1HTR1A | |
| SCHEMBL5656124 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAHTR1AHTR2CCYP3A4 | |
| SCHEMBL3458999 | 0.74 | MAOB (0.52) | SMN1; SMN2LMNACNR2TRPV1CNR1 | |
| SCHEMBL7143641 | 0.74 | LMNA (1.00) | SMN1; SMN2LMNATDP1HDAC6NPC1 | |
| SCHEMBL1302376 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAHTR1AHTR2CNPC1 | |
| SCHEMBL1302329 | 0.70 | — | — | |
| SCHEMBL4407827 | 0.70 | CNR2 (0.56) | SMN1; SMN2CNR2TRPV1CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287438-A1 | Agent for preventing or treating neuropathy | MOMOSE YU | 2008-11-20 | — | — | US | disclosed |
| US-7423159-B2 | Agent for preventing or treating neuropathy | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-09 | — | — | US | disclosed |
| US-20060004069-A1 | Agent for preventing or treating neuropathy | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004069-A1 | Agent for preventing or treating neuropathy | NR2C2, NR0B2, NR2E1 | SMN1; SMN2 75/4885LMNA 2405/4885CNR2 6/4885 |
| US-20080287438-A1 | Agent for preventing or treating neuropathy | NR2C2, NR0B2, NR2E1 | SMN1; SMN2 75/4885LMNA 2405/4885CNR2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.