Dioxane

Dioxane

SCHEMBL3458161

C1COCCO1.Cc1cc(C)cc(C)c1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TSHR P16473 2/20 0.44
TTR P02766 1/20 0.43
LMNA P02545 3/20 0.41
ACHE P22303 1/20 0.37
SMN1; SMN2 Q16637 4/20 0.36
HTT P42858 2/20 0.36
HPGD P15428 1/20 0.36
RAB9A P51151 1/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 2/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.35
CRHBP P24387 2/20 0.35
CRHR2 Q13324 2/20 0.35
TPMT P51580 1/20 0.35
POLB P06746 1/20 0.33
SYK P43405 1/20 0.33
SELL P14151 1/20 0.33
SELP P16109 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL28161889 0.87 ALDH1A1 (0.50) ALDH1A1TSHRLMNAACHESMN1; SMN2
Dioxane SCHEMBL28214980 0.84 TPMT (0.48) ALDH1A1LMNASMN1; SMN2HPGDRAB9A
M-Xylene SCHEMBL5441817 0.82 ACHE (0.67) ALDH1A1LMNAACHESMN1; SMN2HTT
Fluoride SCHEMBL28484697 0.80 ALDH1A1 (0.61) ALDH1A1TSHRACHESMN1; SMN2MAPK1
SCHEMBL28876840 0.79 ALDH1A1 (0.44) ALDH1A1TSHRLMNAACHEMAPT
P-Xylene SCHEMBL27979656 0.79 ACHE (0.57) ALDH1A1TTRLMNAACHESMN1; SMN2
SCHEMBL26115 0.76
SCHEMBL341533 0.76 ALDH1A1 (0.67) ALDH1A1TSHRACHESMN1; SMN2MAPK1
SCHEMBL213952 0.73 ALDH1A1 (0.40) ALDH1A1TSHRLMNAACHEHPGD
Cyclopentane SCHEMBL29049188 0.72 ALDH1A1 (0.53) ALDH1A1TSHRLMNAACHEHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118275513-A Molecularly imprinted electrochemical sensor based on v-COF@SWCNTs-COOH 华南农业大学 2024-07-02 CN claimed
CN-116726994-A Preparation method and application of Salen (M) porous ionic polymer heterogeneous catalyst 昆明理工大学 2023-09-12 CN claimed
CN-112337449-A ZnS-COF/PPy/stainless steel wire solid phase extraction fiber and preparation method thereof 杭州靖舒新材料有限公司 2021-02-09 CN claimed
CN-118325009-A Protonated covalent organic framework material and preparation method and application thereof 清华大学 2024-07-12 CN disclosed
CN-118325010-A Method for improving hydrogen storage performance of covalent organic framework compound and hydrogen storage application thereof 清华大学 2024-07-12 CN disclosed
CN-118275513-A Molecularly imprinted electrochemical sensor based on v-COF@SWCNTs-COOH 华南农业大学 2024-07-02 CN disclosed
US-20240166774-A1 METHOD FOR PREPARING SUPPORTED OLEFIN POLYMERIZATION CATALYST, RESULTING CATALYST AND APPLICATION THEREOF ZHEJIANG UNIVERSITY (CN) 2024-05-23 US disclosed
EP-4273177-A1 METHOD FOR PREPARING SUPPORTED OLEFIN POLYMERIZATION CATALYST, RESULTING CATALYST AND APPLICATION THEREOF Zhejiang University (CN) 2023-11-08 EP disclosed
CN-116726994-A Preparation method and application of Salen (M) porous ionic polymer heterogeneous catalyst 昆明理工大学 2023-09-12 CN disclosed
CN-116726994-A Preparation method and application of Salen (M) porous ionic polymer heterogeneous catalyst 昆明理工大学 2023-09-12 CN disclosed
CN-116685609-A Method for preparing supported olefin polymerization catalyst, catalyst obtained by method and application of catalyst 浙江大学 2023-09-01 CN disclosed
CN-111484602-A Conjugated microporous polymer based on 1,3,6, 8-tetra (p-formylphenyl) pyrene and preparation method thereof 台州学院 2020-08-04 CN disclosed
CN-107540801-B Covalent organic framework and preparation method thereof 中国科学院上海有机化学研究所 2020-07-07 CN disclosed
US-10266634-B2 Chemically stable hollow spherical COF and synthesis thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2019-04-23 US disclosed
CN-107540801-A A kind of covalently organic frame and preparation method thereof 中国科学院上海有机化学研究所 2018-01-05 CN disclosed
US-20170247493-A1 CHEMICALLY STABLE HOLLOW SPERICAL COF AND SYNTHESIS THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2017-08-31 US disclosed
WO-2016030913-A2 CHEMICALLY STABLE HOLLOW SPHERICAL COF AND SYNTHESIS THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-03-03 WO disclosed
US-20100143693-A1 CRYSTALLINE 3D- AND 2D COVALENT ORGANIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-06-10 US disclosed
EP-2114560-A1 CRYSTALLINE 3D- AND 2D-COVALENT ORGANIC FRAMEWORKS The Regents Of The University Of California (US) 2009-11-11 EP disclosed
WO-2008091976-A1 CRYSTALLINE 3D- AND 2D-COVALENT ORGANIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-07-31 WO disclosed