Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459156 | 0.82 | HDAC8 (0.41) | GABRR1HDAC8HDAC6HDAC3HDAC1 | |
| SCHEMBL213654 | 0.80 | — | — | |
| SCHEMBL9051936 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL11564395 | 0.77 | — | — | |
| SCHEMBL28137648 | 0.72 | — | — | |
| SCHEMBL3457631 | 0.71 | HDAC3 (0.44) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| Propane SCHEMBL11669914 | 0.71 | — | — | |
| Formic Acid SCHEMBL31492467 | 0.70 | — | — | |
| SCHEMBL28668791 | 0.70 | — | — | |
| Acetic Acid SCHEMBL180921 | 0.69 | GABRR1 (0.57) | GABRR1LMNACYP2C9GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266953-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | Draximage, Inc. (CA) | 2010-12-29 | — | — | EP | disclosed |
| US-7238339-B2 | Bifunctional chelating compounds containing hydroxamic acid residues | DRAXIS SPECIALTY PHARMACEUTICALS INC. (CA) | 2007-07-03 | — | — | US | disclosed |
| US-20040086460-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | JUBILANT DRAXIMAGE INC. (CA) | 2004-05-06 | — | — | US | disclosed |
| EP-1351926-A2 | NOVEL BIFUNCTIONAL CHELATING COMPOUNDS CONTAINING HYDROXAMIC ACID RESIDUES | Draximage, Inc. (CA) | 2003-10-15 | — | — | EP | disclosed |
| US-6623721-B2 | Conjugates can be complexed to a radioisotope metallic element and used for diagnosing or treating receptor-positive tumors | DRAXIMAGE, INC. (CA) | 2003-09-23 | — | — | US | disclosed |
| WO-2002068379-A2 | NOVEL BIFUNCTIONAL CHELATING COMPOUNDS CONTAINING HYDROXAMIC ACID RESIDUES | DRAXIMAGE, INC. (CA) | 2002-09-06 | — | — | WO | disclosed |
| US-20020076377-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | JUBILANT DRAXIMAGE INC. (CA) | 2002-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020076377-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | EPRS1, HAMP, PHPT1 | GABRR1 2816/4885LMNA 4237/4885HDAC8 525/4885 |
| US-20040086460-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | EPRS1, HAMP, PHPT1 | GABRR1 2816/4885LMNA 4237/4885HDAC8 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.