SCHEMBL3458192

SCHEMBL3458192

CC(=O)C1(Br)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PYGB P11216 8/20 0.43
▸ PYGL P06737 3/20 0.41
▸ PYGM P11217 2/20 0.41
▸ OGA O60502 1/20 0.36
▸ LMNA P02545 1/20 0.35
▸ GBA1 P04062 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8216944 1.00 PYGB (0.43) PYGBPYGLPYGMOGALMNA
SCHEMBL29732640 1.00 PYGB (0.43) PYGBPYGLPYGMOGALMNA
SCHEMBL9296731 1.00 PYGB (0.43) PYGBPYGLPYGMOGALMNA
SCHEMBL8510122 1.00 PYGB (0.43) PYGBPYGLPYGMOGALMNA
SCHEMBL8201558 0.81 PYGB (0.40) PYGBPYGLPYGM
Acetic Acid SCHEMBL30370283 0.81 PYGB (0.42) PYGBPYGLPYGMOGALMNA
SCHEMBL30913907 0.78 MEN1 (0.54) —
SCHEMBL30906670 0.76 PYGB (0.44) PYGBPYGLPYGMOGALMNA
SCHEMBL30536487 0.76 PYGB (0.44) PYGBPYGLPYGMOGALMNA
SCHEMBL3432011 0.76 PYGB (0.44) PYGBPYGLPYGMOGALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220098228-A1 METHODS AND COMPOSITIONS FOR IMPROVING THE IMMUNE SYSTEM AND PROVIDING IMMUNO-PROTECTION NATREON, INC. (US) 2022-03-31 — — US claimed
WO-2022067196-A1 METHODS AND COMPOSITIONS FOR IMPROVING THE IMMUNE SYSTEM AND PROVIDING IMMUNO-PROTECTION NATREON, INC. (US) 2022-03-31 — — WO claimed
WO-2022067196-A1 METHODS AND COMPOSITIONS FOR IMPROVING THE IMMUNE SYSTEM AND PROVIDING IMMUNO-PROTECTION NATREON, INC. (US) 2022-03-31 — — WO disclosed
US-20220098228-A1 METHODS AND COMPOSITIONS FOR IMPROVING THE IMMUNE SYSTEM AND PROVIDING IMMUNO-PROTECTION NATREON, INC. (US) 2022-03-31 — — US disclosed
EP-3390382-A1 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS Ardelyx, Inc. (US) 2018-10-24 — — EP disclosed
WO-2017106818-A1 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS ARDELYX, INC. (US) 2017-06-22 — — WO disclosed
CN-104082294-A Method for using 3-aryl-5-methyl butyrate compound as anti-plant virus agent UNIV HEBEI TECHNOLOGY 2014-10-08 — — CN disclosed
CN-104082294-A Method for using 3-aryl-5-methyl butyrate compound as anti-plant virus agent UNIV HEBEI TECHNOLOGY 2014-10-08 — — CN disclosed
CN-103467463-A Lignin derivatives as well as preparation method and use thereof UNIV NANKAI 2013-12-25 — — CN disclosed
CN-103193769-A 4-methyl-1,2,3-thiadiazole-5-triazole compound as well as preparation method and use thereof UNIV NANKAI 2013-07-10 — — CN disclosed
CN-101157711-B Compound having antineoplastic activity and uses thereof UNIV XIAN JIAOTONG 2010-12-08 — — CN disclosed
WO-2010018438-A2 TETRAZOLE GLYCOSIDES HETERO RESEARCH FOUNDATION (IN) 2010-02-18 — — WO disclosed
CN-100579973-C Process for producing glucal CHENGDU INST BIOLOGY CAS 2010-01-13 — — CN disclosed
CN-101245057-A Process for producing glucal CHENGDU RES INST OF BIOLOGY CH (CN) 2008-08-20 — — CN disclosed
CN-101157711-A Compound having antineoplastic activity and uses thereof UNIV XI AN JIAOTONG (CN) 2008-04-09 — — CN disclosed
US-6878690-B2 Compounds and methods PHARMAXIS PTY LTD. (AU) 2005-04-12 — — US disclosed
EP-1301522-A4 NOVEL COMPOUNDS AND METHODS PHARMAXIS PTY LTD (AU) 2004-04-14 — — EP disclosed
US-20030176363-A1 Novel compounds and methods PHARMAXIS PTY LTD. (AU) 2003-09-18 — — US disclosed
EP-1301522-A1 NOVEL COMPOUNDS AND METHODS Pharmaxis Pty Ltd (AU) 2003-04-16 — — EP disclosed
WO-2002004472-A1 NOVEL COMPOUNDS AND METHODS PHARMAXIS PTY LTD (AU) 2002-01-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220098228-A1 METHODS AND COMPOSITIONS FOR IMPROVING THE IMMUNE SYSTEM AND PROVIDING IMMUNO-PROTECTION UTS2R, DHCR7, CYP8B1 PYGB 709/4885PYGL 549/4885PYGM 1872/4885
US-20030176363-A1 Novel compounds and methods NFATC1, CD4, CCR5 PYGB 1649/4885PYGL 409/4885PYGM 592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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