SCHEMBL3458377

SCHEMBL3458377

CCCCc1ccc(N([C]=O)c2ccc(CCCC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
CA2 P00918 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CA1 P00915 1/20 0.44
RARB P10826 1/20 0.43
PLK1 P53350 1/20 0.43
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ESR1 P03372 2/20 0.41
ADRA2A P08913 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
TACR2 P21452 2/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10013044 0.93 ALDH1A1 (0.52) ALDH1A1HSD17B10CA2RARBTHRA
SCHEMBL10012644 0.88 ESR1 (0.45) ALDH1A1CA2PLK1THRBNPC1
SCHEMBL10012639 0.79 CYP2A6 (0.41) ALDH1A1HPGDCA2SMN1; SMN2PLK1
SCHEMBL10042898 0.79 CA2 (0.59) ALDH1A1HPGDHSD17B10CA2SMN1; SMN2
SCHEMBL5544974 0.78 ALDH1A1 (0.47) ALDH1A1HSD17B10CA2RARBTHRA
SCHEMBL11887127 0.77 CA2 (0.57) ALDH1A1HPGDHSD17B10CA2SMN1; SMN2
SCHEMBL5535192 0.77 ESR1 (0.50) ALDH1A1HSD17B10RARBTHRATHRB
SCHEMBL83869 0.76 CA2 (0.65) ALDH1A1HPGDHSD17B10CA2SMN1; SMN2
SCHEMBL25916996 0.75 CA2 (0.50) ALDH1A1HPGDHSD17B10CA2SMN1; SMN2
SCHEMBL727512 0.75 ALDH1A1 (0.56) ALDH1A1HPGDHSD17B10CA2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-20140001422-A1 COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-02 US disclosed
EP-2478981-A1 SILVER-(CONJUGATED COMPOUND) COMPLEX Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed
EP-2169010-A2 Method of producing organic pigment fine-particles, organic pigment fine-particles obtained thereby, liquid dispersion thereof, and composition thereof FUJIFILM Corporation (JP) 2010-03-31 EP disclosed