Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2175817 | 0.75 | HTR2C (0.60) | HTR2CCTSSCTSKCTSLCTSB | |
| SCHEMBL3458437 | 0.74 | RXRA (0.38) | RXRARXRBRXRGATML3MBTL1 | |
| SCHEMBL2422050 | 0.74 | SIGMAR1 (0.50) | ALDH1A1HTR2C | |
| SCHEMBL16154956 | 0.73 | HTR2C (0.50) | RXRARXRBRXRGATML3MBTL1 | |
| SCHEMBL15842336 | 0.72 | PTPN5 (0.40) | RXRARXRBRXRGATML3MBTL1 | |
| SCHEMBL5352034 | 0.71 | RXRA (0.62) | RXRARXRBRXRGATML3MBTL1 | |
| SCHEMBL8375996 | 0.70 | RXRA (0.42) | RXRARXRBRXRGATML3MBTL1 | |
| SCHEMBL598181 | 0.69 | RXRA (0.66) | RXRARXRBRXRGATML3MBTL1 | |
| SCHEMBL16154953 | 0.69 | HTR2A (0.52) | RXRARXRBRXRGATML3MBTL1 | |
| SCHEMBL19862433 | 0.68 | RXRA (0.41) | RXRARXRBRXRGATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264030-A1 | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | Incyte Corporation (US) | 2010-12-22 | — | — | EP | disclosed |