Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458474 | 0.89 | KMT2A (0.70) | KMT2AHTTRAB9ACD274BCHE | |
| SCHEMBL5113660 | 0.88 | BCHE (0.57) | KMT2AHTTRAB9ACD274BCHE | |
| SCHEMBL14078219 | 0.88 | KMT2A (0.51) | KMT2AHTTRAB9APPARACD274 | |
| SCHEMBL3457501 | 0.82 | HTT (0.65) | KMT2AHTTRAB9ACD274BCHE | |
| SCHEMBL5120825 | 0.82 | BCHE (0.55) | KMT2AHTTRAB9ABCHEMAPT | |
| SCHEMBL5317249 | 0.82 | QPCT (0.48) | KMT2APPARAMEN1KDM4EATM | |
| SCHEMBL5113589 | 0.82 | BCHE (0.69) | KMT2AHTTRAB9ABCHECYP3A4 | |
| SCHEMBL5098443 | 0.80 | KMT2A (0.70) | KMT2AHTTRAB9ACD274BCHE | |
| SCHEMBL17481532 | 0.79 | KMT2A (0.55) | KMT2AHTTRAB9APPARACD274 | |
| SCHEMBL5317502 | 0.78 | KMT2A (0.46) | KMT2AHTTPPARANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |
| WO-2007080109-A1 | SUBSTITUDED BENZYLOXY-PHENYLMETHYLUREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |