Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 13/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317502 | 0.83 | KMT2A (0.46) | PPARAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3458730 | 0.82 | KMT2A (0.55) | PPARAKDM4EMEN1KMT2AATM | |
| SCHEMBL5317248 | 0.82 | TSHR (0.46) | PPARAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5316415 | 0.79 | TSHR (0.49) | PPARAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5113509 | 0.76 | TRPM8 (0.60) | PPARAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5315556 | 0.76 | ALDH1A1 (0.47) | PPARAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14464512 | 0.74 | TRPM8 (0.52) | PPARAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14078285 | 0.74 | TSHR (0.55) | PPARAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14078314 | 0.73 | TRPM8 (0.53) | PPARAKDM4EALDH1A1PTGER1MAPK14 | |
| SCHEMBL5315853 | 0.73 | TRPM8 (0.57) | PPARAKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007080109-A1 | SUBSTITUDED BENZYLOXY-PHENYLMETHYLUREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |